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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H22N2S
Molecular Weight 298.446
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIMEPRAZINE, (R)-

SMILES

C[C@H](CN(C)C)CN1C2=CC=CC=C2SC3=C1C=CC=C3

InChI

InChIKey=ZZHLYYDVIOPZBE-CQSZACIVSA-N
InChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3/t14-/m1/s1

HIDE SMILES / InChI

Molecular Formula C18H22N2S
Molecular Weight 298.446
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
[Inactivation of Trypanosoma cruzi trypanothione reductase by phenothiazine cationic free radicals].
2001 Jan-Mar
Enantioseparation of phenothiazines in capillary zone electrophoresis using cyclodextrins as chiral selectors.
2001 Sep 28
Inactivation of cholinesterase induced by chlorpromazine cation radicals.
2003 Feb
Phenothiazine radicals inactivate Trypanosoma cruzi dihydrolipoamide dehydrogenase: enzyme protection by radical scavengers.
2003 Mar
Antihistamines in the treatment of dermatitis.
2003 Nov-Dec
Acute fatal poisoning with cyamemazine.
2003 Oct 14
Interspecies variability and drug interactions of loxapine metabolism in liver microsomes.
2003 Oct-Dec
Enantioseparation of phenothiazines in cyclodextrin-modified capillary zone electrophoresis: reversal of migration order.
2003 Sep
Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.
2004 Dec
Preliminary studies on phenothiazine-mediated reversal of multidrug resistance in mouse lymphoma and COLO 320 cells.
2005 Nov-Dec
Drop-to-drop solvent microextraction coupled with gas chromatography/mass spectrometry for rapid determination of trimeprazine in urine and blood of rats: application to pharmacokinetic studies.
2007
Large-scale identification of human genes implicated in epidermal barrier function.
2007
Evaluation of enantioselective binding of basic drugs to plasma by ACE.
2007 Aug
Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents.
2007 Dec
[Is alimemazine a suitable sleeping agent for children?].
2008 Oct 9
Influence of comedication on serum concentrations of aripiprazole and dehydroaripiprazole.
2009 Apr
Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.
2009 Jul 14
Development of an ichthyosiform phenotype in Alox12b-deficient mouse skin transplants.
2009 Jun
Are sedatives and hypnotics associated with increased suicide risk of suicide in the elderly?
2009 Jun 4
Management of pain in children with burns.
2010
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010 Dec
Web-based, participant-driven studies yield novel genetic associations for common traits.
2010 Jun 24
Review of therapeutic agents for burns pruritus and protocols for management in adult and paediatric patients using the GRADE classification.
2010 Sep
Large-scale proteomic identification of S100 proteins in breast cancer tissues.
2010 Sep 3
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:05:47 GMT 2023
Edited
by admin
on Sat Dec 16 09:05:47 GMT 2023
Record UNII
5CC6O389DK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRIMEPRAZINE, (R)-
Common Name English
(-)-TRIMEPRAZINE
Systematic Name English
ALIMEMAZINE, (R)-
Common Name English
(-)-ALIMEMAZINE
Systematic Name English
10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, (.BETA.R)-
Systematic Name English
10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, (R)-
Systematic Name English
PHENOTHIAZINE, 10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-, (-)-
Systematic Name English
Code System Code Type Description
FDA UNII
5CC6O389DK
Created by admin on Sat Dec 16 09:05:47 GMT 2023 , Edited by admin on Sat Dec 16 09:05:47 GMT 2023
PRIMARY
PUBCHEM
15558621
Created by admin on Sat Dec 16 09:05:47 GMT 2023 , Edited by admin on Sat Dec 16 09:05:47 GMT 2023
PRIMARY
CAS
2256-27-1
Created by admin on Sat Dec 16 09:05:47 GMT 2023 , Edited by admin on Sat Dec 16 09:05:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID00904832
Created by admin on Sat Dec 16 09:05:47 GMT 2023 , Edited by admin on Sat Dec 16 09:05:47 GMT 2023
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER