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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H22N2S
Molecular Weight 298.446
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRIMEPRAZINE, (R)-

SMILES

C[C@H](CN(C)C)CN1C2=CC=CC=C2SC3=CC=CC=C13

InChI

InChIKey=ZZHLYYDVIOPZBE-CQSZACIVSA-N
InChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3/t14-/m1/s1

HIDE SMILES / InChI

Molecular Formula C18H22N2S
Molecular Weight 298.446
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010-12
Refractory agitation as a marker for pediatric delirium in very young infants at a pediatric intensive care unit.
2010-11
Large-scale proteomic identification of S100 proteins in breast cancer tissues.
2010-09-03
Review of therapeutic agents for burns pruritus and protocols for management in adult and paediatric patients using the GRADE classification.
2010-09
Development of a universal psycho-educational intervention to prevent common postpartum mental disorders in primiparous women: a multiple method approach.
2010-08-18
Significance of S100A2 and S100A4 Expression in the Progression of Prostate Adenocarcinoma.
2010-07
Web-based, participant-driven studies yield novel genetic associations for common traits.
2010-06-24
The study protocol of the Norwegian randomized controlled trial of electroconvulsive therapy in treatment resistant depression in bipolar disorder.
2010-02-23
Management of pain in children with burns.
2010
Intracellular and Extracellular Effects of S100B in the Cardiovascular Response to Disease.
2010
Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.
2009-07-14
Are sedatives and hypnotics associated with increased suicide risk of suicide in the elderly?
2009-06-04
Development of an ichthyosiform phenotype in Alox12b-deficient mouse skin transplants.
2009-06
Influence of comedication on serum concentrations of aripiprazole and dehydroaripiprazole.
2009-04
Simultaneous determination of some phenothiazine derivatives in human blood by headspace solid-phase microextraction and gas chromatography with nitrogen-phosphorus detection.
2009-02-11
Oral midazolam premedication for children undergoing general anaesthesia for dental care.
2009
Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family.
2009
Calcium-binding S100 protein expression in pterygium.
2009
[Is alimemazine a suitable sleeping agent for children?].
2008-10-09
Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.
2008-05-01
A fixed dilated pupil: Pilocarpine: better than a scan.
2008-01-26
[Alimemazine in medical practice].
2008
Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents.
2007-12
Enantioseparation of phenothiazines in CD-modified CZE using single isomer sulfated CD as a chiral selector.
2007-11
Quetiapine and drug interactions: evidence from a routine therapeutic drug monitoring service.
2007-10
The pK(a) Distribution of Drugs: Application to Drug Discovery.
2007-09-17
Evaluation of enantioselective binding of basic drugs to plasma by ACE.
2007-08
Up-regulation of loricrin expression by cell adhesion molecule nectin-1 through Rap1-ERK signaling in keratinocytes.
2007-06-22
Enantioseparation of phenotiazines by affinity electrokinetic chromatography using human serum albumin as chiral selector: application to enantiomeric quality control in pharmaceutical formulations.
2007-01-23
Drop-to-drop solvent microextraction coupled with gas chromatography/mass spectrometry for rapid determination of trimeprazine in urine and blood of rats: application to pharmacokinetic studies.
2007
Large-scale identification of human genes implicated in epidermal barrier function.
2007
Behavioral treatment of bedtime problems and night wakings in infants and young children.
2006-10
Trypanosoma cruzi dihydrolipoamide dehydrogenase as target for phenothiazine cationic radicals. Effect of antioxidants.
2006-09
Determination of trimeprazine-facilitated sedation in children by hair analysis.
2006-07-29
A cluster-randomized educational intervention to reduce inappropriate prescription patterns for elderly patients in general practice--The Prescription Peer Academic Detailing (Rx-PAD) study [NCT00281450].
2006-06-11
[Prescription of psychotropic drugs in paediatry: approved indications and therapeutic perspectives].
2006-01-05
Preliminary studies on phenothiazine-mediated reversal of multidrug resistance in mouse lymphoma and COLO 320 cells.
2005-11-10
Mucosal delivery of cytotoxic therapeutic agents: response of rat nasal mucosa to microencapsulated ethopropazine HCl enantiomer.
2005-11
Effectiveness of alimemazine in controlling retching after Nissen fundoplication.
2005-11
A comparative study on the effects of oral amiodarone and trimeprazine, two in vitro retinyl ester hydrolase inhibitors, on the metabolic availability of vitamin A in rats.
2005-11
Enantioseparation of phenothiazines in cyclodextrin-modified capillary zone electrophoresis using sulfated cyclodextrins as chiral selectors.
2005-10
Antihistamines in the treatment of dermatitis.
2005-06-01
Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex.
2005-05
Cornulin, a new member of the "fused gene" family, is expressed during epidermal differentiation.
2005-05
[Methadone and sleep apnea syndrome].
2005-03
Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.
2004-12
Reversal of an antihistamine-induced coma with flumazenil.
2004-05
Interspecies variability and drug interactions of loxapine metabolism in liver microsomes.
2004-01-28
Acute fatal poisoning with cyamemazine.
2003-10-14
Enantioseparation of phenothiazines in cyclodextrin-modified capillary zone electrophoresis: reversal of migration order.
2003-09
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:29:27 GMT 2025
Edited
by admin
on Mon Mar 31 22:29:27 GMT 2025
Record UNII
5CC6O389DK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRIMEPRAZINE, (R)-
Common Name English
ALIMEMAZINE, (R)-
Preferred Name English
(-)-TRIMEPRAZINE
Systematic Name English
(-)-ALIMEMAZINE
Systematic Name English
10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, (.BETA.R)-
Systematic Name English
10H-PHENOTHIAZINE-10-PROPANAMINE, N,N,.BETA.-TRIMETHYL-, (R)-
Systematic Name English
PHENOTHIAZINE, 10-(3-(DIMETHYLAMINO)-2-METHYLPROPYL)-, (-)-
Systematic Name English
Code System Code Type Description
FDA UNII
5CC6O389DK
Created by admin on Mon Mar 31 22:29:27 GMT 2025 , Edited by admin on Mon Mar 31 22:29:27 GMT 2025
PRIMARY
PUBCHEM
15558621
Created by admin on Mon Mar 31 22:29:27 GMT 2025 , Edited by admin on Mon Mar 31 22:29:27 GMT 2025
PRIMARY
CAS
2256-27-1
Created by admin on Mon Mar 31 22:29:27 GMT 2025 , Edited by admin on Mon Mar 31 22:29:27 GMT 2025
PRIMARY
EPA CompTox
DTXSID00904832
Created by admin on Mon Mar 31 22:29:27 GMT 2025 , Edited by admin on Mon Mar 31 22:29:27 GMT 2025
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER