Simaravibart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:43:01 UTC 2023` Edited by `admin` on `Sat Dec 16 18:43:01 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	5C4T4W973X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Simaravibart

Official Name

English

Immunoglobulin G1 [242-alanine,243-alanine,337-glycine,436-leucine,442-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal MAD0004J08 γ1-chain), disulfide with human monoclonal MAD

Common Name

English

MAD 0004J08 [WHO-DD]

Common Name

English

gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV1-69*08 (95.9%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125)-Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14-49 CH2 A1.3, A1.2, G114, G1v24 CH3 L107, S114 (CH1 R120 (22

Common Name

English

simaravibart [INN]

Common Name

English

simaravibart (immunoglobulin G1-kappa, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody)

Common Name

English

MAD-0004J08

Code

English

Code System Code Type Description

NCI_THESAURUS

C190326

Created by admin on Sat Dec 16 18:43:01 UTC 2023 , Edited by admin on Sat Dec 16 18:43:01 UTC 2023

PRIMARY

CAS

2657609-23-7

Created by admin on Sat Dec 16 18:43:01 UTC 2023 , Edited by admin on Sat Dec 16 18:43:01 UTC 2023

PRIMARY

FDA UNII

5C4T4W973X

Created by admin on Sat Dec 16 18:43:01 UTC 2023 , Edited by admin on Sat Dec 16 18:43:01 UTC 2023

PRIMARY

INN

12423

Created by admin on Sat Dec 16 18:43:01 UTC 2023 , Edited by admin on Sat Dec 16 18:43:01 UTC 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_152	2_208
2_228	4_210
2_269	2_329
1_152	1_208
2_375	2_433
3_23	3_88
3_130	3_190
4_23	4_88
4_130	4_190
1_228	3_210
1_234	2_234
1_237	2_237
1_269	1_329
1_375	1_433

Related Record Type Details


					B6L4N5Z4GH

SARS-COV2

TARGET ORGANISM->INHIBITOR

Amount:

Related Record Type Details


					5C4T4W973X

Simaravibart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL