U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:48:58 GMT 2023
Edited
by admin
on Sat Dec 16 14:48:58 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
5AYQ2F6KU4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE B
Common Name English
CYCLIC GMP-INHIBITED PHOSPHODIESTERASE B
Common Name English
PDE3B
Common Name English
CGIPDE1
Common Name English
Code System Code Type Description
UNIPROT
Q13370
Created by admin on Sat Dec 16 14:48:58 GMT 2023 , Edited by admin on Sat Dec 16 14:48:58 GMT 2023
PRIMARY
FDA UNII
5AYQ2F6KU4
Created by admin on Sat Dec 16 14:48:58 GMT 2023 , Edited by admin on Sat Dec 16 14:48:58 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR->OFF-TARGET
.
INHIBITOR -> TARGET
WEAK INHIBITOR->OFF TARGET
No cardiac toxicity seen in clinical trials
IC50
INHIBITOR->OFF-TARGET
May be responsible for myocarditis and cardiac toxicity
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL