U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 19:46:01 GMT 2023
Edited
by admin
on Sat Dec 16 19:46:01 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Poxviridae
Organism Genus Orthopoxvirus
Organism Species vaccinia virus
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name PSA(L155)-LFA-3/ICAM-1/B7.1
Part WHOLE
Record UNII
59WJ3TGA5K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Rilimogene Galvacirepvec
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
PROSTVAC-V
Code English
Recombinant replicating vaccinia viral vector expressing a modified prostate specific antigen (PSA) plus three co-stimulatory molecules, lymphocyte associated function antigen-3 (LFA-3), intracellular adhesion molecule-1 (ICAM-1) and B7.1
Common Name English
RILIMOGENE GALVACIREPVEC [USAN]
Common Name English
RILIMOGENE GALVACIREPVEC [WHO-DD]
Common Name English
rilimogene galvacirepvec [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2685
Created by admin on Sat Dec 16 19:46:01 GMT 2023 , Edited by admin on Sat Dec 16 19:46:01 GMT 2023
Code System Code Type Description
INN
9622
Created by admin on Sat Dec 16 19:46:01 GMT 2023 , Edited by admin on Sat Dec 16 19:46:01 GMT 2023
PRIMARY
USAN
YY-131
Created by admin on Sat Dec 16 19:46:01 GMT 2023 , Edited by admin on Sat Dec 16 19:46:01 GMT 2023
PRIMARY
FDA UNII
59WJ3TGA5K
Created by admin on Sat Dec 16 19:46:01 GMT 2023 , Edited by admin on Sat Dec 16 19:46:01 GMT 2023
PRIMARY
CAS
1225283-43-1
Created by admin on Sat Dec 16 19:46:01 GMT 2023 , Edited by admin on Sat Dec 16 19:46:01 GMT 2023
PRIMARY
ChEMBL
CHEMBL3039550
Created by admin on Sat Dec 16 19:46:01 GMT 2023 , Edited by admin on Sat Dec 16 19:46:01 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
VECTOR EXPRESSED PROTEIN INTERCELLULAR ADHESION MOLECULE 1 602I13CWRT
VECTOR EXPRESSED PROTEIN T-LYMPHOCYTE ACTIVATION ANTIGEN CD80 W6H7SY78HC
VECTOR EXPRESSED PROTEIN Lymphocyte function-associated antigen 3 ULW3BA7J7W
VECTOR EXPRESSED PROTEIN Rilimogene galvacirepvec expressed prostate-specific antigen (I155L, N196Y) SWH9LGX9PA
VECTOR EXPRESSED PROTEIN T-lymphocyte activation antigen CD80 preprotein APN8654GMB