2,5-DI-TERT-BUTYL-4-METHOXYPHENOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H24O2
Molecular Weight	236.3499
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 2,5-DI-TERT-BUTYL-4-METHOXYPHENOL

Structure Search

SMILES

COC1=CC(=C(O)C=C1C(C)(C)C)C(C)(C)C

InChI

InChIKey=FLLRQABPKFCXSO-UHFFFAOYSA-N

InChI=1S/C15H24O2/c1-14(2,3)10-9-13(17-7)11(8-12(10)16)15(4,5)6/h8-9,16H,1-7H3

HIDE SMILES / InChI

Molecular Formula	C15H24O2
Molecular Weight	236.3499
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4081305
Curator's Comment: The description was created based on several sources, including https://pubs.acs.org/doi/abs/10.1021/ja01611a079

2,6-Di-tert-butyl-4-methoxyphenol is a phenolic antioxidant, that has been used to protect cosmetics from oxidative degradation. 2,6-Di-tert-butyl-4-methoxyphenol is used as a food additive, preservative in food packaging, animal feed, rubber, and petroleum products. Dietary administration of 2,6-di-tert-butyl-4-methoxyphenol resulted in complete protection against the lung toxicity of butylated hydroxytoluene in mice.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Protective effects of butylated hydroxyanisole and its analogs on the lung toxicity of butylated hydroxytoluene in mice.	1985-10	4081305

Patents

Sample Use Guides

In Vivo Use Guide

Mice weretreated with 11.1 or 27.7 micromol/g diet for 3 days

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:30:42 GMT 2025` Edited by `admin` on `Mon Mar 31 19:30:42 GMT 2025`
Record UNII	593E9T2MWH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,5-DI-TERT-BUTYL-4-METHOXYPHENOL

Systematic Name

English

2,5-DI-TERT-BUTYL-4-HYDROXYANISOLE

Preferred Name

English

PHENOL, 2,5-BIS(1,1-DIMETHYLETHYL)-4-METHOXY-

Systematic Name

English

PHENOL, 2,5-DI-TERT-BUTYL-4-METHOXY-

Systematic Name

English

Code System Code Type Description

CAS

1991-52-2