izastobart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 16:49:58 GMT 2023` Edited by `admin` on `Sat Dec 16 16:49:58 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	58R5Z64YQ6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

izastobart

Official Name

English

Immunoglobulin G1 [234-alanine,235-glutamic acid,237-alanine,330-serine,331-serine], anti-(human C5a anaphylatoxin chemotactic receptor 1) (human monoclonal TJ210001 γ1-chain), disulfide with human monoclonal TJ210001 λ-chain, dimer

Common Name

English

Gamma1 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-15*07 (92.9%) -(IGHD) -IGHJ3*01 (92.9%) M123>L(114), CDR-IMGT [8.10.10] (26-33.51-60.99-108)) (1-119)-Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v43 CH2 A1.3, E1.2, A1, G1v

Common Name

English

TJ-210001

Code

English

Immunoglobulin G1-lambda, anti-[Homo sapiens C5AR1 (complement C5a receptor 1, C5R1, CD88)], Homo sapiens monoclonal antibody

Common Name

English

TJ210001

Code

English

izastobart [INN]

Common Name

English

Code System Code Type Description

FDA UNII

58R5Z64YQ6

Created by admin on Sat Dec 16 16:49:58 GMT 2023 , Edited by admin on Sat Dec 16 16:49:58 GMT 2023

PRIMARY

CAS

2769937-42-8

Created by admin on Sat Dec 16 16:49:58 GMT 2023 , Edited by admin on Sat Dec 16 16:49:58 GMT 2023

PRIMARY

INN

12721

Created by admin on Sat Dec 16 16:49:58 GMT 2023 , Edited by admin on Sat Dec 16 16:49:58 GMT 2023

PRIMARY

From	To
4_137	4_196
4_22	4_89
3_137	3_196
3_22	3_89
2_369	2_427
2_263	2_323
2_222	4_214
2_146	2_202
2_22	2_98
1_369	1_427
1_263	1_323
1_231	2_231
1_228	2_228
1_222	3_214
1_146	1_202
1_22	1_98

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					O73AZS73V4

C5A ANAPHYLATOXIN

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					58R5Z64YQ6

izastobart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL