U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Tc.H3O9P3
Molecular Weight 338.846
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TECHNETIUM TC-99M TRIMETAPHOSPHATE

SMILES

[99Tc].OP1(=O)OP(O)(=O)OP(O)(=O)O1

InChI

InChIKey=QHIFPWMJUHNMMK-IEOVAKBOSA-N
InChI=1S/H3O9P3.Tc/c1-10(2)7-11(3,4)9-12(5,6)8-10;/h(H,1,2)(H,3,4)(H,5,6);/i;1+1

HIDE SMILES / InChI

Molecular Formula H3O9P3
Molecular Weight 239.9397
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Tc
Molecular Weight 98.9063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
OSTEOLITE

Approved Use

Unknown

Launch Date

1977
Diagnostic
DRAXIMAGE MDP-10

Approved Use

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

Launch Date

1978
PubMed

PubMed

TitleDatePubMed
Future of low specific activity molybdenum-99/technetium-99m generator.
2012 Oct
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:06:08 GMT 2023
Edited
by admin
on Sat Dec 16 09:06:08 GMT 2023
Record UNII
57ZK50IG20
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TECHNETIUM TC-99M TRIMETAPHOSPHATE
Common Name English
METAPHOSPHORIC ACID (H3P3O9), TECHNETIUM-99TC SALT
Systematic Name English
Code System Code Type Description
CAS
63804-10-4
Created by admin on Sat Dec 16 09:06:08 GMT 2023 , Edited by admin on Sat Dec 16 09:06:08 GMT 2023
PRIMARY
PUBCHEM
138394028
Created by admin on Sat Dec 16 09:06:08 GMT 2023 , Edited by admin on Sat Dec 16 09:06:08 GMT 2023
PRIMARY
FDA UNII
57ZK50IG20
Created by admin on Sat Dec 16 09:06:08 GMT 2023 , Edited by admin on Sat Dec 16 09:06:08 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY