U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H10O2
Molecular Weight 114.1424
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CAPROLACTONE

SMILES

O=C1CCCCCO1

InChI

InChIKey=PAPBSGBWRJIAAV-UHFFFAOYSA-N
InChI=1S/C6H10O2/c7-6-4-2-1-3-5-8-6/h1-5H2

HIDE SMILES / InChI

Molecular Formula C6H10O2
Molecular Weight 114.1424
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester) triblock copolymers and putrescine: synthesis, characterization and cytocompatibility.
2004-01
Subchondral bone reaction associated with chondral defect and attempted cartilage repair in goats.
2004-01
Using PC12 cells to evaluate poly(caprolactone) and collagenous microcarriers for applications in nerve guide fabrication.
2003-12-06
In vivo behavior of poly(1,3-trimethylene carbonate) and copolymers of 1,3-trimethylene carbonate with D,L-lactide or epsilon-caprolactone: Degradation and tissue response.
2003-12-01
Synthesis of poly(epsilon-caprolactone)-b-poly(gamma-benzyl-L-glutamic acid) block copolymer using amino organic calcium catalyst.
2003-11-11
Synthesis of the star-shaped copolymer of epsilon-caprolactone and L-lactide from a cyclotriphosphazene core.
2003-11-11
Mechanistic limitations in the synthesis of polyesters by lipase-catalyzed ring-opening polymerization.
2003-10-05
Structure and mechanical properties of poly(D,L-lactic acid)/poly(epsilon -caprolactone) blends.
2003-10
Mechanistic study of Bu2SnCl2-mediated ring-opening polymerization of epsilon-caprolactone by multinuclear NMR spectroscopy.
2003-09-22
Poly lactic acid--caprolactone copolymer tube with a denatured skeletal muscle segment inside as a guide for peripheral nerve regeneration: a morphological and electrophysiological evaluation of the regenerated nerves.
2003-09
Tepidiphilus margaritifer gen. nov., sp. nov., isolated from a thermophilic aerobic digester.
2003-09
Polymeric carriers for amphotericin B: in vitro activity, toxicity and therapeutic efficacy against systemic candidiasis in neutropenic mice.
2003-09
Osteoblast growth and function in porous poly epsilon -caprolactone matrices for bone repair: a preliminary study.
2003-09
Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) block copolymers: characterization and their use as drug carriers for a controlled delivery system.
2003-09
Qualitative and quantitative solid-phase microextraction gas chromatographic-mass spectrometric determination of the low-molecular-mass compounds released from poly(vinyl chloride)/polycaprolactone-polycarbonate during ageing.
2003-08-22
Biodegradation of poly(epsilon-caprolactone)/starch blends and composites in composting and culture environments: the effect of compatibilization on the inherent biodegradability of the host polymer.
2003-08-12
Preparation of macroporous biodegradable poly(L-lactide-co-epsilon-caprolactone) foams and characterization by mercury intrusion porosimetry, image analysis, and impedance spectroscopy.
2003-08-01
Osteogenic induction of human bone marrow-derived mesenchymal progenitor cells in novel synthetic polymer-hydrogel matrices.
2003-08
Structural characterization of a lipase-catalyzed copolymerization of epsilon-caprolactone and D,L-lactide.
2003-07-15
Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering.
2003-07-01
[Study on the binary blends of poly(epsilon-caprolactone) with different cellulose derivatives by infrared spectra].
2003-06
[Encapsulation of atrial natriuretic peptide (ANP) cDNA transfection cells and ANP circadian expression].
2003-06
Surfactant-free microspheres of poly(epsilon-caprolactone)/poly (ethylene glycol)/poly(epsilon-caprolactone) triblock copolymers as a protein carrier.
2003-06
A prolonged immune response to antigen delivered in poly (epsilon-caprolactone) microparticles.
2003-06
Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)-poly(ethylene oxide)-polylactide amphiphilic copolymer nanoparticles.
2003-06
Photoinitiated crosslinked degradable copolymer networks for tissue engineering applications.
2003-06
Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(epsilon-caprolactone) copolymer as a carrier for paclitaxel.
2003-05-20
A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering.
2003-05
Biodegradation-based polymer surface erosion and surface renewal for foul-release at low ship speeds.
2003-04
Investigation of nanocomposites based on semi-interpenetrating network of [L-poly (epsilon-caprolactone)]/[net-poly (epsilon-caprolactone)] and hydroxyapatite nanocrystals.
2003-04
Study of emulsion stabilization by graft copolymers using the optical analyzer Turbiscan.
2003-03-18
Stereospecific synthesis of chiral caprolactone monomers from D-glucose.
2003-03-14
Surface modification of tricalcium phosphate for improvement of the interfacial compatibility with biodegradable polymers.
2003-03
Biodegradable elastomeric scaffolds for soft tissue engineering.
2003-02-21
Comparison of chitosan and gelatin coated microparticles: prepared by hot-melt method.
2003-01-30
Effect of pressure and temperature upon tin alkoxide-promoted ring-opening polymerisation of epsilon-caprolactone in supercritical carbon dioxide.
2003-01-21
Polycaprolactone-poly(ethylene glycol) multiblock copolymers as potential substitutes for di(ethylhexyl) phthalate in flexible poly(vinyl chloride) formulations.
2003-01-14
Atovaquone-loaded nanocapsules: influence of the nature of the polymer on their in vitro characteristics.
2003-01-02
Growth factor releasing porous poly (epsilon-caprolactone)-chitosan matrices for enhanced bone regenerative therapy.
2003-01
Functionalization of poly-(L-lactic-co-epsilon-caprolactone): effects of surface modification on endothelial cell proliferation and hemocompatibility [corrected].
2003
Laser-perforated membranous biomaterials induced pore size-dependent bone induction when used as a new BMP carrier.
2003
BHK cell attachment and growth on EDA-plasma-modified poly(L-lactide/epsilon-caprolactone) biodegradable films.
2003
Preclinical development of biodegradable polymer foils for intracerebral delivery of cytotoxic nucleosides.
2003
Creating bioabsorbable Schwann cell coated conduits through tissue engineering.
2003
Cellular uptake and concentrations of tamoxifen upon administration in poly(epsilon-caprolactone) nanoparticles.
2003
Acid-initiated polymerization of epsilon-caprolactone under microwave irradiation and its application in the preparation of drug controlled release system.
2003
Amphiphilic copolymers of epsilon-caprolactone and gamma-substituted epsilon-caprolactone. Synthesis and functionalization of poly(D,L-lactide) nanoparticles.
2003
Poly(D, L-lactide/epsilon-caprolactone)/hydroxyapatite composites as bone filler: an in vivo study in rats.
2002-12
Homoleptic lanthanide complexes of chelating bis(phosphanyl)amides: synthesis, structure, and ring-opening polymerization of lactones.
2002-11-15
The metabolism of cyclohexanol by Acinetobacter NCIB 9871.
1975-12-01
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:46:53 GMT 2025
Edited
by admin
on Mon Mar 31 18:46:53 GMT 2025
Record UNII
56RE988L1R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EPSILON-CAPROLACTONE
INCI  
Preferred Name English
CAPROLACTONE
HSDB  
Common Name English
.EPSILON.-CAPROLACTONE
Common Name English
HEXANOIC ACID, 6-HYDROXY-, .EPSILON.-LACTONE
Common Name English
CAPROLACTONE, EPSILON-
Common Name English
.EPSILON.-HEXANOLACTONE
Common Name English
HEXAN-6-OLIDE
Common Name English
PLACCEL M
Brand Name English
CAPROLACTONE [HSDB]
Common Name English
2-OXEPANONE
Systematic Name English
TONE ECEQ
Brand Name English
Code System Code Type Description
RXCUI
1998122
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
PRIMARY
FDA UNII
56RE988L1R
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
PRIMARY
HSDB
5670
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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ECHA (EC/EINECS)
207-938-1
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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CAS
502-44-3
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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EPA CompTox
DTXSID4027159
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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DAILYMED
56RE988L1R
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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CHEBI
17915
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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PUBCHEM
10401
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
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WIKIPEDIA
CAPROLACTONE
Created by admin on Mon Mar 31 18:46:53 GMT 2025 , Edited by admin on Mon Mar 31 18:46:53 GMT 2025
PRIMARY