DPI 201-106 BISMESYLATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C29H30N4O2.2CH4O3S
Molecular Weight	658.785
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CS(O)(=O)=O.CS(O)(=O)=O.OC(COC1=CC=CC2=C1C=C(N2)C#N)CN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5

InChI

InChIKey=OOSRZNZCOSLOFK-UHFFFAOYSA-N

InChI=1S/C29H30N4O2.2CH4O3S/c30-19-24-18-26-27(31-24)12-7-13-28(26)35-21-25(34)20-32-14-16-33(17-15-32)29(22-8-3-1-4-9-22)23-10-5-2-6-11-23;2*1-5(2,3)4/h1-13,18,25,29,31,34H,14-17,20-21H2;2*1H3,(H,2,3,4)

HIDE SMILES / InChI

Molecular Formula	C29H30N4O2
Molecular Weight	466.5741
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	CH4O3S
Molecular Weight	96.106
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
voltage-gated Na+ channels 2 Target ID: voltage-gated Na+ channels Sources: https://www.ncbi.nlm.nih.gov/pubmed/18953087 \| https://www.ncbi.nlm.nih.gov/pubmed/19524054	Modulator 828

PubMed

Title	Date	PubMed
Evidence for state-dependent block of DPI 201-106, a synthetic inhibitor of Na+ channel inactivation, on delayed-rectifier K+ current in pituitary tumor (GH3) cells.	2008 Sep	18953087
Models of torsades de pointes: effects of FPL64176, DPI201106, dofetilide, and chromanol 293B in isolated rabbit and guinea pig hearts.	2009 Sep-Oct	19524054

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:53:30 UTC 2023` Edited by `admin` on `Fri Dec 15 15:53:30 UTC 2023`
Record UNII	55P62ZYF1K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DPI 201-106 BISMESYLATE

Code

English

4-(3-(4-(DIPHENYLMETHYL)-1-PIPERAZINYL)-2-HYDROXYPROPOXY)-1H-INDOLE-2-CARBONITRILE BISMESYLATE

Systematic Name

English

Code System Code Type Description

CAS

78573-15-6

Created by admin on Fri Dec 15 15:53:30 UTC 2023 , Edited by admin on Fri Dec 15 15:53:30 UTC 2023

NON-SPECIFIC STOICHIOMETRY

FDA UNII

55P62ZYF1K

Created by admin on Fri Dec 15 15:53:30 UTC 2023 , Edited by admin on Fri Dec 15 15:53:30 UTC 2023

PRIMARY

PUBCHEM

131801055

Created by admin on Fri Dec 15 15:53:30 UTC 2023 , Edited by admin on Fri Dec 15 15:53:30 UTC 2023

PRIMARY

Related Record Type Details


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DPI-201-106

PARENT -> SALT/SOLVATE