Pemivibart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:48:41 GMT 2023` Edited by `admin` on `Sat Dec 16 19:48:41 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	557S3L3FAP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Pemivibart

Official Name

English

Immunoglobulin G1 [435-leucine,441-alanine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal VYD222 γ1-chain), disulfide with human monoclonal VYD222 λ2-chain, dimer

Common Name

English

gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-21*07 (88.8%) -(IGHD) -IGHJ4*01(92.9%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1R120, CH3 E12, M14, G1v78 L107, A114 (CH1 R120(221) (125-222),

Common Name

English

immunoglobulin G1-lambda2, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody

Common Name

English

pemivibart [INN]

Common Name

English

Code System Code Type Description

INN

13017

Created by admin on Sat Dec 16 19:48:41 GMT 2023 , Edited by admin on Sat Dec 16 19:48:41 GMT 2023

PRIMARY

FDA UNII

557S3L3FAP

Created by admin on Sat Dec 16 19:48:41 GMT 2023 , Edited by admin on Sat Dec 16 19:48:41 GMT 2023

PRIMARY

CAS

2858673-18-2

Created by admin on Sat Dec 16 19:48:41 GMT 2023 , Edited by admin on Sat Dec 16 19:48:41 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_151	2_207
2_227	4_217
2_268	2_328
1_151	1_207
2_374	2_432
3_22	3_90
3_140	3_199
4_22	4_90
4_140	4_199
1_227	3_217
1_233	2_233
1_236	2_236
1_268	1_328
1_374	1_432

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_304
N	2_304

Related Record Type Details


					557S3L3FAP

Pemivibart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL