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Details

Stereochemistry EPIMERIC
Molecular Formula C24H34O4
Molecular Weight 386.5244
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROLIGESTONE

SMILES

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@]5(CC[C@@]24OC(CC)O5)C(C)=O

InChI

InChIKey=MQSDUYIXZDSLSZ-QSDCUGRSSA-N
InChI=1S/C24H34O4/c1-5-20-27-23(15(2)25)12-13-24(28-20)19-7-6-16-14-17(26)8-10-21(16,3)18(19)9-11-22(23,24)4/h14,18-20H,5-13H2,1-4H3/t18-,19+,20?,21-,22+,23-,24+/m0/s1

HIDE SMILES / InChI

Molecular Formula C24H34O4
Molecular Weight 386.5244
Charge 0
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 6 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Proligestone is a pregnane derivative patented by Koninklijke Nederlandsche Gist-en Spiritusfabriek N. V. As a progestin medication for veterinary medicine. Proligestone is used to control estrus in dogs and cats and has also been used to treat hypersexuality in dogs and cats. Administration of progestins in the dog may result in overproduction of growth hormone, suppression of the hypothalamic-pituitary-adrenocortical axis, and insulin resistance.

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparison of the histological changes in the dog after treatment with the progestins medroxyprogesterone acetate and proligestone.
1995 Dec
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 16:17:26 GMT 2023
Edited
by admin
on Fri Dec 15 16:17:26 GMT 2023
Record UNII
55772LJ01V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROLIGESTONE
INN   MART.  
INN  
Official Name English
proligestone [INN]
Common Name English
PROLIGESTONE [MI]
Common Name English
COVINAN
Brand Name English
PROLIGESTONE [MART.]
Common Name English
DELVOSTERON
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C776
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
Code System Code Type Description
WIKIPEDIA
PROLIGESTONE
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
CAS
23873-85-0
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
MESH
C017677
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
EVMPD
SUB10081MIG
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
SMS_ID
100000081143
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
NCI_THESAURUS
C77016
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
ChEMBL
CHEMBL2106696
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
FDA UNII
55772LJ01V
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
PUBCHEM
71906
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
MERCK INDEX
m12136
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
INN
3287
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
ECHA (EC/EINECS)
245-922-6
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
EPA CompTox
DTXSID501016687
Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY