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Details

Stereochemistry EPIMERIC
Molecular Formula C24H34O4
Molecular Weight 386.5244
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROLIGESTONE

SMILES

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@]5(CC[C@@]24OC(CC)O5)C(C)=O

InChI

InChIKey=MQSDUYIXZDSLSZ-QSDCUGRSSA-N
InChI=1S/C24H34O4/c1-5-20-27-23(15(2)25)12-13-24(28-20)19-7-6-16-14-17(26)8-10-21(16,3)18(19)9-11-22(23,24)4/h14,18-20H,5-13H2,1-4H3/t18-,19+,20?,21-,22+,23-,24+/m0/s1

HIDE SMILES / InChI

Molecular Formula C24H34O4
Molecular Weight 386.5244
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 6 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Proligestone is a pregnane derivative patented by Koninklijke Nederlandsche Gist-en Spiritusfabriek N. V. As a progestin medication for veterinary medicine. Proligestone is used to control estrus in dogs and cats and has also been used to treat hypersexuality in dogs and cats. Administration of progestins in the dog may result in overproduction of growth hormone, suppression of the hypothalamic-pituitary-adrenocortical axis, and insulin resistance.

Originator

Approval Year

PubMed

Patents

Substance Class Chemical
Record UNII
55772LJ01V
Record Status Validated (UNII)
Record Version