Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H10N2 |
| Molecular Weight | 146.1891 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC2=C(C=C1C)N=CN2
InChI
InChIKey=LJUQGASMPRMWIW-UHFFFAOYSA-N
InChI=1S/C9H10N2/c1-6-3-8-9(4-7(6)2)11-5-10-8/h3-5H,1-2H3,(H,10,11)
| Molecular Formula | C9H10N2 |
| Molecular Weight | 146.1891 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Assessment of the existence of hyper-long axial Co(II)-N bonds in cobinamide B(12) models by using electron paramagnetic resonance spectroscopy. | 2001 Apr 11 |
|
| Molecular modeling of the mechanochemical triggering mechanism for catalysis of carbon-cobalt bond homolysis in coenzyme B12. | 2001 Jan 15 |
|
| Thermodynamic and kinetic studies on the reaction between the vitamin B12 derivative beta-(N-methylimidazolyl)cobalamin and N-methylimidazole: ligand displacement at the alpha axial site of cobalamins. | 2001 Mar 26 |
|
| Enzymatic activity of coenzyme B(12) derivatives with altered axial nucleotides: probing the mechanochemical triggering hypothesis in ribonucleotide reductase. | 2001 Nov 5 |
|
| Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica. | 2001 Oct 5 |
|
| Equilibrium and kinetic studies on the reactions of alkylcobalamins with cyanide. | 2001 Oct 8 |
|
| Renal interstitial cGMP mediates natriuresis by direct tubule mechanism. | 2001 Sep |
|
| Synthesis of adenosylcobinamide 2-chlorophenyl phosphate, a zwitterionic cobinamide phosphate analog of adenosylcobalamin en route to crystallizable cobinamides. | 2002 Aug 15 |
|
| The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol. | 2002 Sep |
|
| Alpha-5,6-dimethylbenzimidazole adenine dinucleotide (alpha-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium. | 2003 Apr |
|
| Cobalamin-dependent methionine synthase: probing the role of the axial base in catalysis of methyl transfer between methyltetrahydrofolate and exogenous cob(I)alamin or cob(I)inamide. | 2003 Dec 16 |
|
| Reactions of nitric oxide with vitamin B12 and its precursor, cobinamide. | 2003 Jul 29 |
|
| Formation of the dimethylbenzimidazole ligand of coenzyme B(12) under physiological conditions by a facile oxidative cascade. | 2003 Jun 26 |
|
| Spectroscopic and computational studies of Co3+-corrinoids: spectral and electronic properties of the B12 cofactors and biologically relevant precursors. | 2003 May 14 |
|
| Solution structure and thermolysis of Cobeta-5'-deoxyadenosylimidazolylcobamide, a coenzyme B12 analogue with an imidazole axial nucleoside. | 2004 Dec 13 |
|
| Spectroscopic and computational studies on the adenosylcobalamin-dependent methylmalonyl-CoA mutase: evaluation of enzymatic contributions to Co-C bond activation in the Co3+ ground state. | 2004 Jul 7 |
|
| Differentiation of ionised benzimidazole from its isomeric alpha-distonic ion by collision-induced dissociation and neutralisation-reionisation mass spectrometry. | 2005 |
|
| The enzymatic activation of coenzyme B12. | 2006 Mar 7 |
|
| X-ray structural characterization of imidazolylcobalamin and histidinylcobalamin: cobalamin models for aquacobalamin bound to the B12 transporter protein transcobalamin. | 2007 Apr 30 |
|
| BluB cannibalizes flavin to form the lower ligand of vitamin B12. | 2007 Mar 22 |
|
| Biochemistry: molecular cannibalism. | 2007 Mar 22 |
|
| Analysis of vibrational spectra of 5,6-dimethyl benzimidazole based on density functional theory calculations. | 2007 Nov |
|
| Pseudovitamin B(12) is the corrinoid produced by Lactobacillus reuteri CRL1098 under anaerobic conditions. | 2007 Oct 16 |
|
| Medical implications of benzimidazole derivatives as drugs designed for targeting DNA and DNA associated processes. | 2008 |
|
| Identification of metabolites with anticancer properties by computational metabolomics. | 2008 Jun 17 |
|
| Metabolism of halophilic archaea. | 2008 Mar |
|
| Ag4L2 nanocage as a building unit toward the construction of silver metal strings. | 2008 Nov 17 |
|
| Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. | 2009 Apr 14 |
|
| The cobinamide amidohydrolase (cobyric acid-forming) CbiZ enzyme: a critical activity of the cobamide remodelling system of Rhodobacter sphaeroides. | 2009 Dec |
|
| [Effect of a corrinoid on Methanosarcina barkeri DNA synthesis]. | 2009 Jan-Feb |
|
| (N-n-Butyl-pyridine-4-carbothio-amide-κN)chloridobis(dimethyl-glyoximato-κN,N')cobalt(III) hemihydrate. | 2009 Jun 20 |
|
| Stabilization of the base-off forms of vitamin B(12) and coenzyme B(12) by encapsulation of the alpha-axial 5,6-dimethylbenzimidazole ligand with cucurbit[7]uril. | 2009 May 14 |
|
| Structure-based mechanism of ADP-ribosylation by sirtuins. | 2009 Nov 27 |
|
| Apparent ruminal synthesis and intestinal disappearance of vitamin B12 and its analogs in dairy cows. | 2009 Sep |
|
| Sirtuin chemical mechanisms. | 2010 Aug |
|
| (E)-1,2-Bis(1-propyl-5,6-dimethyl-1H-benzimidazol-2-yl)ethene. | 2010 Feb 10 |
|
| Purification and some properties of wild-type and N-terminal-truncated ethanolamine ammonia-lyase of Escherichia coli. | 2010 Jan |
|
| Thermolability of mutant MMACHC protein in the vitamin B12-responsive cblC disorder. | 2010 May |
|
| Toxicology and drug delivery by cucurbit[n]uril type molecular containers. | 2010 May 6 |
|
| Redetermination of the X-ray structure of nitroxylcobalamin: base-on nitroxylcobalamin exhibits a remarkably long Co-N(dimethylbenzimidazole) bond distance. | 2010 Nov 28 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:04:59 GMT 2023
by
admin
on
Fri Dec 15 19:04:59 GMT 2023
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| Record UNII |
553XI1DS20
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| Record Status |
Validated (UNII)
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| Record Version |
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582-60-5
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553XI1DS20
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675
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C015158
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Dimethylbenzimidazole
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m4528
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DB02591
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209-488-1
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68316
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15890
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DTXSID70870631
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