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Details

Stereochemistry ACHIRAL
Molecular Formula C6H15ClSi
Molecular Weight 150.722
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of tert-Butyldimethylchlorosilane

SMILES

CC(C)(C)[Si](C)(C)Cl

InChI

InChIKey=BCNZYOJHNLTNEZ-UHFFFAOYSA-N
InChI=1S/C6H15ClSi/c1-6(2,3)8(4,5)7/h1-5H3

HIDE SMILES / InChI
Molecular Formula C6H15ClSi
Molecular Weight 150.722
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Synthesis and structure-activity relationship of 3-O-acylated (-)-epigallocatechins as 5α-reductase inhibitors.
2010-12
A practical Delta 1-dehydrogenation of Delta 4-3-keto-steroids with DDQ in the presence of TBDMSCl at room temperature.
2010-07
A ratiometric fluorescent probe for fluoride ion employing the excited-state intramolecular proton transfer.
2009-11-15
Development and validation of a gas chromatography/mass spectrometry method for the assessment of genomic DNA methylation.
2009-09
Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks.
2009-04
Uric acid is a mediator of the Plasmodium falciparum-induced inflammatory response.
2009
2-(Benzoyl-amino-meth-yl)pyridinium chloride.
2008-11-13
N-[3-(tert-Butyl-dimethyl-siloxymeth-yl)-5-nitro-phen-yl]acetamide.
2008-09-27
Solid phase microextraction procedure for the determination of alkylphenols in water by on-fiber derivatization with N-tert-butyl-dimethylsilyl-N-methyltrifluoroacetamide.
2008-08-29
N-methylation of the c3' amide of taxanes: synthesis of N-methyltaxol C and N-methylpaclitaxel.
2008-06-20
Derivatization of organophosphorus nerve agent degradation products for gas chromatography with ICPMS and TOF-MS detection.
2007-06
Novel fluorogenic probe for fluoride ion based on the fluoride-induced cleavage of tert-butyldimethylsilyl ether.
2007-06
Regioselective and stereospecific amination of iridoids: conversion of aucubin into aminoside antibiotic analogues.
2007-01
A fluorescein-based fluorogenic probe for fluoride ion based on the fluoride-induced cleavage of tert-butyldimethylsilyl ether.
2007-01
Syntheses of 19-[O-(carboxymethyl)oxime] haptens of epipregnanolone and pregnanolone.
2006-02
Synthesis of 6I-amino-6I-deoxy-2I-VII,3I-VII-tetradeca-O-methyl-cyclomaltoheptaose.
2004-05-17
Synthesis of D-altritol nucleosides with a 3'-O-tert-butyldimethylsilyl protecting group.
2004
Synthesis of 2'-O-substituted ribonucleosides.
2003-10-21
Analysis of O,S-dimethyl hydrogen phosphorothioate in urine, a specific biomarker for methamidophos.
2003-10-08
Identification of a novel family of nucleosides that specifically inhibit HIV-1 reverse transcriptase.
2001-12-03
Sorption of nonpolar aromatic contaminants by chlorosilane surface modified natural minerals.
2001-11-01
Patents

Patents

04171431
2
04224336
1
04290947
1
04348320
3
04616007
1
04689349
1
04696929
1
04732912
1
04820817
1
04857652
1
04931463
1
04959391
1
04965274
1
04983723
2
04985435
1
04987141
1
05003087
1
05004739
1
05013827
1
05051505
10
05061718
2
05068339
1
05089495
1
05098932
1
05102877
3
05117042
1
05122523
2
05132420
6
05132422
1
05144045
5
05149696
1
05149699
3
05151512
6
05177202
1
05196542
1
05208223
2
05219881
1
05221671
2
05233031
2
05240920
6
05245085
1
05246931
6
05246944
1
05252565
1
05254676
1
05258537
1
05264586
1
05272171
4
05290771
2
05290780
2
05318972
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:41:36 GMT 2025
Edited
by admin
on Mon Mar 31 20:41:36 GMT 2025
Record UNII
550OPF5Z9F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
T-BUME2SICL
Preferred Name English
tert-Butyldimethylchlorosilane
MI  
Systematic Name English
CHLORO(1,1-DIMETHYLETHYL)DIMETHYLSILANE
Systematic Name English
TBDMS CHLORIDE
Common Name English
CHLORODIMETHYL-TERT-BUTYLSILANE
Systematic Name English
TERT-BUTYLCHLORODIMETHYLSILANE
Systematic Name English
TBDMS-CL
Common Name English
TBS-CL
Common Name English
TERT-BUTYLDIMETHYLSILYL CHLORIDE
Systematic Name English
TERT-BUTYLDIMETHYLCHLOROSILANE [MI]
Common Name English
TERT-BUTYL(DIMETHYL)SILANE CHLORIDE
Systematic Name English
2-(CHLORODIMETHYLSILYL)-2-METHYLPROPANE
Systematic Name English
SILANE, CHLORO(1,1-DIMETHYLETHYL)DIMETHYL-
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID4038843
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
CAS
18162-48-6
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
FDA UNII
550OPF5Z9F
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
ECHA (EC/EINECS)
242-042-4
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
CHEBI
85071
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
MERCK INDEX
m2837
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
tert-Butyldimethylsilyl chloride
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
PUBCHEM
28928
Created by admin on Mon Mar 31 20:41:36 GMT 2025 , Edited by admin on Mon Mar 31 20:41:36 GMT 2025
PRIMARY
NIH
NCATS
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