Cyclin T1-CDK9 COMPLEX

Substance Class	Protein Created by `admin` on `Wed Apr 02 14:34:24 GMT 2025` Edited by `admin` on `Wed Apr 02 14:34:24 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	54R8HTX3CU
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

CDK9-Cyclin T1 COMPLEX

Preferred Name

English

P-TEFb

Common Name

English

Code System Code Type Description

FDA UNII

54R8HTX3CU

Created by admin on Wed Apr 02 14:34:24 GMT 2025 , Edited by admin on Wed Apr 02 14:34:24 GMT 2025

PRIMARY

Related Record Type Details


					1GAJ98SC2X

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					9EK26WE8QN

INHIBITOR -> TARGET

Amount:


					MKS45S912B

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					0W9Q8U337A

INHIBITOR -> TARGET

Amount:

Modification Type	Location Site	Location Type	Residue Modified	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_416] [1_474] [1_475] [1_531] [1_549] [1_552] [1_563] [1_637]	SITE_SPECIFIC	S	ADP-RIBOSYLSERINE	64GZ4K5DPK
AMINO_ACID_SUBSTITUTION	[2_350] [2_354] [2_362] [2_363]	SITE_SPECIFIC	T	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[1_390]	SITE_SPECIFIC	K	N6-ACETYLLYSINE	470AD5VY1X
AMINO_ACID_SUBSTITUTION	[1_117] [1_340] [1_388] [1_495] [1_499] [1_564] [1_577] [2_175] [2_353] [2_357]	SITE_SPECIFIC	S	DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL