Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H17NO4 |
| Molecular Weight | 203.2356 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC(=O)CC[C@H](N)C(=O)OCC
InChI
InChIKey=HERPVHLYIHBEFW-ZETCQYMHSA-N
InChI=1S/C9H17NO4/c1-3-13-8(11)6-5-7(10)9(12)14-4-2/h7H,3-6,10H2,1-2H3/t7-/m0/s1
| Molecular Formula | C9H17NO4 |
| Molecular Weight | 203.2356 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The internal state of medium spiny neurons varies in response to different input signals. | 2010-03-17 |
|
| Nicotine stimulation of the medulla increases blood flow of the common carotid artery in cats. | 2010-01-15 |
|
| Glutamate release upon purinergic action in the dorsal facial area of the medulla increases blood flow in the common carotid artery in cats. | 2009-10-20 |
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| Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents. | 2009-08-13 |
|
| Synthesis and evaluation of novel organogermanium sesquioxides as antitumor agents. | 2009 |
|
| Nitric oxide and glutamate in the dorsal facial area regulate common carotid blood flow in the cat. | 2008-10-10 |
|
| Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates. | 2008-09-25 |
|
| [Synthesis of diethyl N-[p-(methylamino)benzoyl]-L-glutamate]. | 2008-08-18 |
|
| Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester. | 2008-06 |
|
| Alcohol related changes in regulation of NMDA receptor functions. | 2008-03 |
|
| Synthesis of (-)-Indolizidine 167B based on domino hydroformylation/cyclization reactions. | 2008-01-15 |
|
| Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors. | 2008-01-10 |
|
| Synthesis of N-(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5-substituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-l-glutamic acid diethyl ester: evaluation of in vitro anti-cancer and anti-folate activities. | 2008-01 |
|
| Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates. | 2007-06-28 |
|
| DARPP-32 is a robust integrator of dopamine and glutamate signals. | 2006-12-22 |
|
| Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidine as antifolates. | 2006-12-15 |
|
| The blockade of AMPA-kainate and NMDA receptors in the dorsal periaqueductal gray reduces the effects of diazepam withdrawal in rats. | 2006-12-08 |
|
| Dual inhibitors of thymidylate synthase and dihydrofolate reductase as antitumor agents: design, synthesis, and biological evaluation of classical and nonclassical pyrrolo[2,3-d]pyrimidine antifolates(1). | 2006-02-09 |
|
| Activation by N-acetyl-L-aspartate of acutely dissociated hippocampal neurons in rats via metabotropic glutamate receptors. | 2003-09 |
|
| [The role of non-NMDA glutamate receptors in the EEG effects of chronic administration of noopept GVS-111 in awake rats]. | 2003-02-25 |
|
| Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol. | 2002-11-08 |
|
| Glutamatergic and serotonergic mechanisms in the dorsal facial area for common carotid artery blood flow control in the cat. | 2002-10-31 |
|
| Mouse cerebellar adenosine-glutamate interactions and modulation of ethanol-induced motor incoordination. | 2002-09 |
|
| Synthesis of N-[4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid as an antifolate. | 2002-04-25 |
|
| Protease-catalyzed regioselective polymerization and copolymerization of glutamic acid diethyl ester. | 2002-03-13 |
|
| Primary neurotransmitters and regulatory substances onto vestibular nucleus neurons. | 2001-12 |
|
| Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat. | 2001-11 |
|
| Excitation of rat striatal large neurons by dopamine and/or glutamate released from nerve terminals via presynaptic nicotinic receptor (A4beta2 type) stimulation. | 2001-08 |
|
| beta-NAAG rescues LTP from blockade by NAAG in rat dentate gyrus via the type 3 metabotropic glutamate receptor. | 2001-03 |
|
| [Rheologic infusion therapy, neurotransmitter administration and lidocaine injection in tinnitus. A staged therapeutic concept]. | 2001-02 |
|
| NAAG inhibits KCl-induced [(3)H]-GABA release via mGluR3, cAMP, PKA and L-type calcium conductance. | 2001-01 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:54:20 GMT 2025
by
admin
on
Mon Mar 31 19:54:20 GMT 2025
|
| Record UNII |
54QM1L3N85
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| Record Status |
Validated (UNII)
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| Record Version |
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Official Name | English | ||
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Preferred Name | English | ||
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| Code System | Code | Type | Description | ||
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16450-41-2
Created by
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DTXSID90167772
Created by
admin on Mon Mar 31 19:54:20 GMT 2025 , Edited by admin on Mon Mar 31 19:54:20 GMT 2025
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54QM1L3N85
Created by
admin on Mon Mar 31 19:54:20 GMT 2025 , Edited by admin on Mon Mar 31 19:54:20 GMT 2025
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73961
Created by
admin on Mon Mar 31 19:54:20 GMT 2025 , Edited by admin on Mon Mar 31 19:54:20 GMT 2025
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PRIMARY |