5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-amine

NC1=C2N=C(C=CN2N=C1)N3CCC[C@@H]3C4=CC(F)=CC=C4F

InChIKey=PNTNLXBVYHOZQI-CQSZACIVSA-N

InChI=1S/C16H15F2N5/c17-10-3-4-12(18)11(8-10)14-2-1-6-22(14)15-5-7-23-16(21-15)13(19)9-20-23/h3-5,7-9,14H,1-2,6,19H2/t14-/m1/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Substance Class	Chemical Created by `admin` on `Wed Apr 02 14:25:01 GMT 2025` Edited by `admin` on `Wed Apr 02 14:25:01 GMT 2025`
Record UNII	54Q4FL3GH3
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-amine

Systematic Name

English

Larotrectinib DFP-PPPA Impurity

Preferred Name

English

Pyrazolo[1,5-a]pyrimidin-3-amine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-

Systematic Name

English

(R)-5-(2-(2,5-Difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine

Systematic Name

English

Code System Code Type Description

CAS

1223404-88-3

Created by admin on Wed Apr 02 14:25:01 GMT 2025 , Edited by admin on Wed Apr 02 14:25:01 GMT 2025

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FDA UNII

54Q4FL3GH3

Created by admin on Wed Apr 02 14:25:01 GMT 2025 , Edited by admin on Wed Apr 02 14:25:01 GMT 2025

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PUBCHEM

58386314

Created by admin on Wed Apr 02 14:25:01 GMT 2025 , Edited by admin on Wed Apr 02 14:25:01 GMT 2025

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