U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2022
324
Substance Class Protein
Created
by admin
on Tue Apr 01 20:39:54 GMT 2025
Edited
by admin
on Tue Apr 01 20:39:54 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
54534MX6Z9
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
Teclistamab
USAN   INN  
Official Name English
JNJ-64007957
Preferred Name English
TECLISTAMAB [USAN]
Common Name English
Teclistamab [WHO-DD]
Common Name English
immunoglobulin G4-lambda, anti-[Homo sapiens TNFRSF17 (TNF receptor superfamily member 17, tumor necrosis factor receptor superfamily, member 17, B cell maturation antigen, BCMA, BCM, TNFRSF13A, CD269)] and anti-[Homo sapiens CD3 epsilon (CD3E, Leu-4)],
Common Name English
teclistamab [INN]
Common Name English
Immunoglobulin G4 [233-proline, 239-alanine, 240-alanine, 410-leucine], anti- (human CD3 antigen) (human monoclonal JNJ-63483043 ?4-chain), disulfide with human monoclonal JNJ-63483043 ?-chain,(231?227'),(234?230')- bis(disulfide) with immunoglobulin G4
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 782920
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
Code System Code Type Description
FDA UNII
54534MX6Z9
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
INN
10928
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
NCI_THESAURUS
C136823
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
SMS_ID
300000005901
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
CAS
2119595-80-9
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
RXCUI
2619426
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
USAN
JK-142
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
DAILYMED
54534MX6Z9
Created by admin on Tue Apr 01 20:39:54 GMT 2025 , Edited by admin on Tue Apr 01 20:39:54 GMT 2025
PRIMARY
From To
1_22 1_97
1_148 1_204
1_262 1_322
1_368 1_426
2_22 2_98
2_152 2_208
2_266 2_326
2_372 2_430
3_22 3_87
3_136 3_195
4_22 4_90
4_137 4_196
1_135 3_213
2_139 4_214
1_227 2_231
1_230 2_234
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_302
Related Record Type Details
TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17
TARGET -> INHIBITOR
BINDING
Teclistamab-CQYV
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
Teclistamab
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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