U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:10:20 GMT 2023
Edited
by admin
on Sat Dec 16 15:10:20 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
53YMC3A1CU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Surzebiclimab
USAN   INN  
Official Name English
BGB-A425
Code English
surzebiclimab [INN]
Common Name English
BGBA425
Code English
SURZEBICLIMAB [USAN]
Common Name English
Immunoglobulin G1 [235-proline,236-alanine,237-alanine,de-239-glycine,331-alanine], anti-(human hepatitis A virus cellular receptor 2) (human-Mus musculus monoclonal BGB-A425 γ1-chain), disulfide with human-Mus musculus monoclonal BGB-A425 κ-chain, dim
Common Name English
BGB A425 [WHO-DD]
Common Name English
ANTI-TIM-3 MONOCLONAL ANTIBODY BGB-A425
Common Name English
Immunoglobulin G1-kappa, anti-[Homo sapiens HAVCR2 (hepatitis A virus cellular receptor 2, T-cell immunoglobulin mucin family member 3, Tim-3, TIM3, TIMD3, CD366)], monoclonal antibody; gamma1 heavy chain (1-448) [VH (Homo sapiens IGHV3-23*04 (93.8%) -(I
Common Name English
Code System Code Type Description
CAS
2342597-90-2
Created by admin on Sat Dec 16 15:10:20 GMT 2023 , Edited by admin on Sat Dec 16 15:10:20 GMT 2023
PRIMARY
NCI_THESAURUS
C157242
Created by admin on Sat Dec 16 15:10:20 GMT 2023 , Edited by admin on Sat Dec 16 15:10:20 GMT 2023
PRIMARY NCIT
INN
11453
Created by admin on Sat Dec 16 15:10:20 GMT 2023 , Edited by admin on Sat Dec 16 15:10:20 GMT 2023
PRIMARY INN
USAN
KL-130
Created by admin on Sat Dec 16 15:10:20 GMT 2023 , Edited by admin on Sat Dec 16 15:10:20 GMT 2023
PRIMARY
FDA UNII
53YMC3A1CU
Created by admin on Sat Dec 16 15:10:20 GMT 2023 , Edited by admin on Sat Dec 16 15:10:20 GMT 2023
PRIMARY
From To
1_22 1_95
1_146 1_202
1_222 3_218
1_228 2_228
1_231 2_231
1_262 1_322
1_368 1_426
2_22 2_95
2_146 2_202
2_222 4_218
2_262 2_322
2_368 2_426
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL