U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:51:29 GMT 2023
Edited
by admin
on Sat Dec 16 15:51:29 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
5384HK7574
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
TRASTUZUMAB DERUXTECAN
INN  
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 (METASTATIC LYMPH NODE GENE 19 PROTEIN, PROTO-ONCOGENE C-ERBB-2, CD340 ANTIGEN))HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO DERUXTECAN, A CAMPTOTHECIN DERIVATIVE AND A LI
Systematic Name English
TRASTUZUMAB DERUXTECAN [JAN]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN TYROSINE KINASE RECEPTOR ERBB2) (HUMAN-MUS MUSCULUS MONOCLONAL DS20151130 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL DS20151130 LIGHT CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1
Systematic Name English
TRASTUZUMAB DERUXTECAN [USAN]
Common Name English
Trastuzumab deruxtecan [WHO-DD]
Common Name English
trastuzumab deruxtecan [INN]
Common Name English
DS-8201
Code English
Classification Tree Code System Code
NCI_THESAURUS C1512
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
FDA ORPHAN DRUG 738420
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
NCI_THESAURUS C129823
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
Code System Code Type Description
FDA UNII
5384HK7574
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
WIKIPEDIA
Trastuzumab deruxtecan
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
NCI_THESAURUS
C152716
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
NO STRUCTURE GIVEN
DAILYMED
5384HK7574
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
LACTMED
Trastuzumab Deruxtecan
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
RXCUI
2267582
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
CAS
1826843-81-5
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
USAN
GH-79
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
DRUG BANK
DB14962
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
RXCUI
2267574
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
ALTERNATIVE
SMS_ID
100000174462
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
NCI_THESAURUS
C128799
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
INN
10516
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
DRUG CENTRAL
5367
Created by admin on Sat Dec 16 15:51:29 GMT 2023 , Edited by admin on Sat Dec 16 15:51:29 GMT 2023
PRIMARY
From To
2_223 4_214
1_223 3_214
1_22 1_96
1_147 1_203
1_264 1_324
1_370 1_428
2_22 2_96
2_147 2_203
2_264 2_324
2_370 2_428
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_229 2_229
1_232 2_232
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
SUB_CONCEPT->SUBSTANCE
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT(CALCULATED) CHEMICAL