RANUZIFIGENE CIVAPARVOVEC

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 04:13:48 GMT 2025` Edited by `admin` on `Wed Apr 02 04:13:48 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependovirus
Organism Species	adeno-associated virus
Author	NONE
Infraspecific Type	SUBSTRAIN
Infraspecific Name	rAAV Rep2-Cap6/ expressing a cDNA that targets 468-485 bp of the albumin locus fused to the obligate heterodimeric FokI nuclease domainELD, under the control of an apolipoprotein E hepatic control region and human alpha-1-antitrypsin promoter (ApoE/hAAT)
Part	whole
Record UNII	52XT2AZD2N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RANUZIFIGENE CIVAPARVOVEC

Official Name

English

ranuzifigene civaparvovec [INN]

Preferred Name

English

A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, EXPRESSING A CDNA THAT TARGETS 468-485 BP OF THE ALBUMIN LOCUS (RELATIVE TO THE TRANSCRIPTION INITIATION SITE), FUSED TO THE OBLIGATE HETERODIMERIC FOKI NUCLEASE DOMAI

Systematic Name

English

Code System Code Type Description

NCI_THESAURUS

C171801