Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C11H15N5O5 |
| Molecular Weight | 297.2673 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C=[N+]([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C3=C1C(=O)NC([NH-])=N3
InChI
InChIKey=OGHAROSJZRTIOK-KQYNXXCUSA-N
InChI=1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1
| Molecular Formula | C11H15N5O5 |
| Molecular Weight | 297.2673 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Monitoring of urinary excretion of modified nucleosides in cancer patients using a set of six monoclonal antibodies. | 1992 Jan 31 |
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| Mechanism and regulation of translation in C. elegans. | 2006 Jan 28 |
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| Non-adenine based purines accelerate wound healing. | 2006 Nov |
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| Interactions of calf spleen purine nucleoside phosphorylase with formycin B and its aglycone - spectroscopic and kinetic studies. | 2007 |
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| Solid-supported synthesis of 5'-mRNA CAP-4 from Trypanosomatids. | 2007 |
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| Identification of modified residues in RNAs by reverse transcription-based methods. | 2007 |
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| The major 5' end of HIV type 1 RNA corresponds to G456. | 2007 Aug |
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| Transcriptional networking cap-tures the 7SK RNA 5'-gamma-methyltransferase. | 2007 Aug 17 |
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| MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans. | 2007 Sep 17 |
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| Systematic identification of non-coding RNA 2,2,7-trimethylguanosine cap structures in Caenorhabditis elegans. | 2007 Sep 29 |
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| m7GTP alphaS is a strong and stable inhibitor of cap-dependent translation. | 2008 |
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| The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon. | 2008 Aug 20 |
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| Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase. | 2008 Dec 15 |
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| Biochemical characterization of Yin Yang 1-RNA complexes. | 2008 Feb |
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| Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code. | 2008 Jul 30 |
|
| MicroRNA: An emerging therapeutic target and intervention tool. | 2008 Jun |
|
| Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS. | 2008 Jun |
|
| Stacking efficiency and flexibility analysis of aromatic amino acids in cap-binding proteins. | 2008 Jun |
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| Detection and localization of small nuclear ribonucleoproteins (snRNPs) in trypanosomatids using anti-m3G antibodies. | 2008 Mar |
|
| Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. | 2008 May 15 |
|
| Motor step size and ATP coupling efficiency of the dsDNA translocase EcoR124I. | 2008 May 7 |
|
| snoRNA, a novel precursor of microRNA in Giardia lamblia. | 2008 Nov |
|
| The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis. | 2008 Nov |
|
| Identifying intrinsic and extrinsic determinants that regulate internal initiation of translation mediated by the FMR1 5' leader. | 2008 Oct 15 |
|
| Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode. | 2008 Oct 17 |
|
| MicroRNA profiling and head and neck cancer. | 2009 |
|
| The RNA polymerase dictates ORF1 requirement and timing of LINE and SINE retrotransposition. | 2009 Apr |
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| Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. | 2009 Apr 1 |
|
| Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection. | 2009 Apr 5 |
|
| Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. | 2009 Aug |
|
| microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells. | 2009 Aug 27 |
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| Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma. | 2009 Aug 4 |
|
| Influenza A: understanding the viral life cycle. | 2009 Dec |
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| Regulation of mRNA cap methylation. | 2009 Dec 23 |
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| Thermodynamic analysis of mRNA cap binding by the human initiation factor eIF4E via free energy perturbations. | 2009 Dec 23 |
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| EBNA3C interacts with Gadd34 and counteracts the unfolded protein response. | 2009 Dec 29 |
|
| Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex. | 2009 Jan 16 |
|
| The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif. | 2009 Jan 21 |
|
| Mechanisms employed by retroviruses to exploit host factors for translational control of a complicated proteome. | 2009 Jan 24 |
|
| Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer. | 2009 Jan 9 |
|
| PcrA helicase tightly couples ATP hydrolysis to unwinding double-stranded DNA, modulated by the initiator protein for plasmid replication, RepD. | 2009 Jul 14 |
|
| Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. | 2009 Jul 23 |
|
| The GTPase activity of Escherichia coli FtsZ determines the magnitude of the FtsZ polymer bundling by ZapA in vitro. | 2009 Nov 24 |
|
| Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa. | 2009 Nov 5 |
|
| Comparative analysis of an experimental subcellular protein localization assay and in silico prediction methods. | 2009 Oct |
|
| Identification of gemin5 as a novel 7-methylguanosine cap-binding protein. | 2009 Sep 14 |
|
| TERRA: telomeric repeat-containing RNA. | 2009 Sep 2 |
|
| Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles. | 2010 Feb 1 |
|
| Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition. | 2010 Jan |
|
| The Arc of synaptic memory. | 2010 Jan |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 11:45:10 GMT 2023
by
admin
on
Sat Dec 16 11:45:10 GMT 2023
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| Record UNII |
5290OM2I6G
|
| Record Status |
Validated (UNII)
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| Record Version |
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19702
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6474236
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DTXSID30942368
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7-Methylguanosine
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20794
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5290OM2I6G
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20244-86-4
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DB03493
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