Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H12O3 |
| Molecular Weight | 144.1684 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=C)C(=O)OCCCO
InChI
InChIKey=GNSFRPWPOGYVLO-UHFFFAOYSA-N
InChI=1S/C7H12O3/c1-6(2)7(9)10-5-3-4-8/h8H,1,3-5H2,2H3
| Molecular Formula | C7H12O3 |
| Molecular Weight | 144.1684 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Hyperbranched polyamidoamines containing beta-cyclodextrin for controlled release of chlorambucil. | 2009-11-10 |
|
| Nortriptyline for smoking cessation: release and human skin diffusion from patches. | 2009-08-13 |
|
| Evaluation of pharmacokinetics of bioreducible gene delivery vectors by real-time PCR. | 2009-07 |
|
| HPMA-based polymer conjugates with drug combination. | 2009-06-28 |
|
| N-(2-hydroxypropyl)methacrylamide-amphotericin B (HPMA-AmB) copolymer conjugates as antileishmanial agents. | 2009-05 |
|
| Biorecognition and subcellular trafficking of HPMA copolymer-anti-PSMA antibody conjugates by prostate cancer cells. | 2009-04-07 |
|
| Cetuximab retargeting of adenovirus via the epidermal growth factor receptor for treatment of intraperitoneal ovarian cancer. | 2009-03 |
|
| Self-assembling diblock copolymers of poly[N-(2-hydroxypropyl)methacrylamide] and a beta-sheet peptide. | 2009-01-09 |
|
| Feasibility of using a bone-targeted, macromolecular delivery system coupled with prostaglandin E(1) to promote bone formation in aged, estrogen-deficient rats. | 2008-12 |
|
| Synthesis and evaluation of a well-defined HPMA copolymer-dexamethasone conjugate for effective treatment of rheumatoid arthritis. | 2008-12 |
|
| From defined reactive diblock copolymers to functional HPMA-based self-assembled nanoaggregates. | 2008-11 |
|
| One-pot conversion of RAFT-generated multifunctional block copolymers of HPMA to doxorubicin conjugated acid- and reductant-sensitive crosslinked micelles. | 2008-11 |
|
| HPMA copolymer-doxorubicin-gadolinium conjugates: synthesis, characterization, and in vitro evaluation. | 2008-08-11 |
|
| Synthesis and biological evaluation of disulfide-linked HPMA copolymer-mesochlorin e6 conjugates. | 2008-05-13 |
|
| Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: in vitro effect of extra drug-free GlyPheLeuGly sequences. | 2008-04-21 |
|
| New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting. | 2008-04-21 |
|
| Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs. | 2008-03-03 |
|
| Dynamic light scattering study of self-assembly of HPMA hybrid graft copolymers. | 2008-02 |
|
| Biodegradable, cationic methacrylamide-based polymers for gene delivery to ovarian cancer cells in mice. | 2008-01-10 |
|
| Campylobacter jejuni survives within epithelial cells by avoiding delivery to lysosomes. | 2008-01 |
|
| Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specific HPMA copolymer-9-AC conjugate in rats. | 2008-01 |
|
| Stability in plasmas of various species of HPMA copolymer-PGE1 conjugates. | 2007-12 |
|
| [Pilot study of a cell membrane like biomimetic drug-eluting coronary stent]. | 2007-06 |
|
| Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems. | 2007-02-26 |
|
| Biodistribution and pharmacokinetics of colon-specific HPMA copolymer--9-aminocamptothecin conjugate in mice. | 2007-02-12 |
|
| Designing polymer conjugates as lysosomotropic nanomedicines. | 2007-02 |
|
| Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis. | 2007 |
|
| Affinity separation of immunoglobulin G subclasses on dye attached poly(hydroxypropyl methacrylate) beads. | 2006-11-15 |
|
| Macrophage targeted N-(2-hydroxypropyl)methacrylamide conjugates for magnetic resonance imaging. | 2006-10-03 |
|
| Properties of HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer chain modification. | 2006-09-28 |
|
| Polymeric conjugates of mono- and bi-cyclic alphaVbeta3 binding peptides for tumor targeting. | 2006-08-28 |
|
| Enhancement of ethyl propionate synthesis by poly (AAc-co-HPMA-cl-MBAm)-immobilized Pseudomonas aeruginosa MTCC-4713, exposed to Hg2+ and NH4+ ions. | 2006-06 |
|
| Hybrid hydrogels self-assembled from HPMA copolymers containing peptide grafts. | 2006-03-14 |
|
| Colon-specific 9-aminocamptothecin-HPMA copolymer conjugates containing a 1,6-elimination spacer. | 2006-01-10 |
|
| Polymer-peptide conjugates for angiogenesis targeted tumor radiotherapy. | 2006-01 |
|
| Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers. | 2005-12-10 |
|
| Ultrasound-enhanced transfection activity of HPMA-stabilized DNA polyplexes with prolonged plasma circulation. | 2005-09-02 |
|
| Targeting tumor angiogenesis: comparison of peptide and polymer-peptide conjugates. | 2005-09 |
|
| Induction of systemic antitumour resistance with targeted polymers. | 2005-07 |
|
| Polymer therapeutics designed for a combination therapy of hormone-dependent cancer. | 2005-06-27 |
|
| Water-soluble polymers for targeted drug delivery to human squamous carcinoma of head and neck. | 2005-04 |
|
| Intracellular targeting of polymer-bound drugs for cancer chemotherapy. | 2005-02-28 |
|
| Improved preservation of X-gal reaction product for electron microscopy using hydroxypropyl methacrylate. | 2005-02-01 |
|
| Oligopeptides as targeting structures in cancer theraPY. | 2005-01-03 |
|
| Final report of the safety assessment of methacrylate ester monomers used in nail enhancement products. | 2005 |
|
| The arthrotropism of macromolecules in adjuvant-induced arthritis rat model: a preliminary study. | 2004-10 |
|
| Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. | 2004-10 |
|
| Aggregation properties of a HPMA-camptothecin copolymer in isotonic solutions. | 2004-08-01 |
|
| A novel crosslinkable polymer as drug-loaded coating for biomedical device. | 2004-02 |
|
| HPMA copolymer-1,5-diazaanthraquinone conjugates as novel anticancer therapeutics. | 2004 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:51:13 GMT 2025
by
admin
on
Mon Mar 31 17:51:13 GMT 2025
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| Record UNII |
523A6318HJ
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| Record Status |
Validated (UNII)
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| Record Version |
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220-426-2
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17694
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2761-09-3
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DTXSID0062630
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