RILOTUMUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:38:28 GMT 2025` Edited by `admin` on `Mon Mar 31 20:38:28 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2
Sequence Origin	HUMAN
Record UNII	51WEW898IJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AMG 102

Preferred Name

English

RILOTUMUMAB

Official Name

English

IMMUNOGLOBULIN G2, ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR) (HUMAN MONOCLONAL 2.12.1 HEAVY CHAIN), DISULPHIDE WITH HUMAN MONOCLONAL 2.12.1 LIGHT CHAIN, DIMER

Common Name

English

AMG-102

Code

English

RILOTUMUMAB [USAN]

Common Name

English

IMMUNOGLOBULIN G2, ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR) (HUMAN MONOCLONAL 2.12.1 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL 2.12.1 LIGHT CHAIN, DIMER

Common Name

English

rilotumumab [INN]

Common Name

English

Rilotumumab [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129822

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

FDA ORPHAN DRUG

369412

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

EU-Orphan Drug

EU/3/14/1291

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

Code System Code Type Description

CAS

872514-65-3

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

SMS_ID

100000126110

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

NCI_THESAURUS

C67079

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

ChEMBL

CHEMBL1743063

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

EVMPD

SUB33146

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

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DRUG BANK

DB11972

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

FDA UNII

51WEW898IJ

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

USAN

SS-81

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

MESH

C524459

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

INN

9123

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

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WIKIPEDIA

RILOTUMUMAB

Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025

PRIMARY

From	To
1_22	1_95
1_147	1_203
1_260	1_320
1_366	1_424
2_22	2_95
2_147	2_203
2_260	2_320
2_366	2_424
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_134	3_215
2_134	4_215
1_222	2_222
1_223	2_223
1_226	2_226
1_229	2_229

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					QA085PMU8Q

HEPATOCYTE GROWTH FACTOR RECEPTOR

TARGET -> INHIBITOR

Comments:

Blocks HGF binding to receptor.

Amount:


					BEI7G52Q8Z

HUMAN HEPATOCYTE GROWTH FACTOR

TARGET -> INHIBITOR

Comments:

Binds and blocks binding to Met receptor

Amount:

Related Record Type Details


					51WEW898IJ

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL