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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 20:38:28 GMT 2025
Edited
by admin
on Mon Mar 31 20:38:28 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMAN
Record UNII
51WEW898IJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMG 102
Preferred Name English
RILOTUMUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
IMMUNOGLOBULIN G2, ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR) (HUMAN MONOCLONAL 2.12.1 HEAVY CHAIN), DISULPHIDE WITH HUMAN MONOCLONAL 2.12.1 LIGHT CHAIN, DIMER
Common Name English
AMG-102
Code English
RILOTUMUMAB [USAN]
Common Name English
IMMUNOGLOBULIN G2, ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR) (HUMAN MONOCLONAL 2.12.1 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL 2.12.1 LIGHT CHAIN, DIMER
Common Name English
rilotumumab [INN]
Common Name English
Rilotumumab [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129822
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
FDA ORPHAN DRUG 369412
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
EU-Orphan Drug EU/3/14/1291
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
Code System Code Type Description
CAS
872514-65-3
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
SMS_ID
100000126110
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
NCI_THESAURUS
C67079
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
ChEMBL
CHEMBL1743063
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
EVMPD
SUB33146
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
DRUG BANK
DB11972
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
FDA UNII
51WEW898IJ
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
USAN
SS-81
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
MESH
C524459
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
INN
9123
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
WIKIPEDIA
RILOTUMUMAB
Created by admin on Mon Mar 31 20:38:28 GMT 2025 , Edited by admin on Mon Mar 31 20:38:28 GMT 2025
PRIMARY
From To
1_22 1_95
1_147 1_203
1_260 1_320
1_366 1_424
2_22 2_95
2_147 2_203
2_260 2_320
2_366 2_424
3_23 3_88
3_135 3_195
4_23 4_88
4_135 4_195
1_134 3_215
2_134 4_215
1_222 2_222
1_223 2_223
1_226 2_226
1_229 2_229
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
HEPATOCYTE GROWTH FACTOR RECEPTOR
TARGET -> INHIBITOR
Blocks HGF binding to receptor.
HUMAN HEPATOCYTE GROWTH FACTOR
TARGET -> INHIBITOR
Binds and blocks binding to Met receptor
Related Record Type Details
RILOTUMUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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