U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Polyglactin 910, is a synthetic absorbable suture which has been synthesized by the copolymerization of a mixture of purified lactide and glycolide which are cyclic intermediates derived from lactic and glycolic acids. It is degraded by Chemical Hydrolysis, that later is absorbed and metabolized by the human body. The absorption process is followed by a mass loss and fully absorbed in 90 days. The rate of absorption of polyglactin 910 is not appreciably affected by contaminated wounds. The strength and handling polyglactin 910 are similar to those of polyglycolic acid but the knot security decreases with the coating. Polyglactin 910 causes less visible reactions in the feline linea alba than polydioxanone and surgical gut do.

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparison of non-absorbable silk and absorbable polyglactin sutures for external ptosis repair.
2020-02
A Retrospective Review of Vaginal Cuff Dehiscence: Comparing Absorbable and Nonabsorbable Sutures.
2020-01
Securing extraocular muscles in strabismus surgery: effect of cautery on suture strength.
2019-10
Polyglactin 910 suture compared with polyglactin 910 coated with triclosan in dental implant surgery: randomized clinical trial.
2019-10
In Vivo Feasibility of Arterial Embolization with Permanent and Absorbable Suture: The FAIR-Embo Concept.
2019-08
In vitro evaluation of the knot-holding capacity and security, weight, and volume of forwarder knots tied with size-3 polyglactin 910 suture exposed to air, balanced electrolyte solution, or equine abdominal fat.
2019-07
[Study on the mechanical properties of sutures in the process of suturing].
2019-06-25
Management of cleft lip and palate in Egypt: A National survey.
2019-04-16
Relationship between serum glycolate and falsely elevated lactate in severe ethylene glycol poisoning.
2009-04
Patents
Substance Class Polymer
Created
by admin
on Mon Mar 31 23:29:01 GMT 2025
Edited
by admin
on Mon Mar 31 23:29:01 GMT 2025
Record UNII
51L8Z461QZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VICRYL
VANDF  
Preferred Name English
POLYGLACTIN 910
USAN  
USAN  
Official Name English
VICRYL [VANDF]
Common Name English
L-Lactide and Glycolide (10:90) Copolymer 80000 Acid
Common Name English
POLYGLACTIN 910 [USAN]
Common Name English
XLG
Common Name English
POLY(L-LACTIDE-CO-GLYCOLIDE; 1:9, MW 80000)
Common Name English
Code System Code Type Description
ChEMBL
CHEMBL2108539
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
PRIMARY
CAS
385434-35-5
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
GENERIC (FAMILY)
FDA UNII
51L8Z461QZ
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
PRIMARY
CHEBI
53493
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
PRIMARY
SMS_ID
100000176817
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
PRIMARY
CAS
26780-50-7
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
ALTERNATIVE
NCI_THESAURUS
C166803
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
PRIMARY
MESH
D011098
Created by admin on Mon Mar 31 23:29:01 GMT 2025 , Edited by admin on Mon Mar 31 23:29:01 GMT 2025
PRIMARY
Display Structure of POLYGLACTIN 910
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:WEIGHT AVERAGE CHEMICAL