DEMATIRSEN

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 16:42:30 GMT 2023` Edited by `admin` on `Sat Dec 16 16:42:30 GMT 2023`
Nucleic Acid Subtype
Sequence Type	OLIGONUCLEOTIDE
Record UNII	51FM0REX6F
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

DEMATIRSEN

Official Name

English

dematirsen [INN]

Common Name

English

RNA, (P-THIO)(GM-UM-UM-GM-M5CM-M5CM-UM-M5CM-M5CM-GM-GM-UM-UM-M5CM-UM-GM-AM-AM-GM-GM-UM-GM-UM-UM-M5CM)

Systematic Name

English

Code System Code Type Description

CAS

1802465-55-9

Created by admin on Sat Dec 16 16:42:30 GMT 2023 , Edited by admin on Sat Dec 16 16:42:30 GMT 2023

PRIMARY

NCI_THESAURUS

C166802

Created by admin on Sat Dec 16 16:42:30 GMT 2023 , Edited by admin on Sat Dec 16 16:42:30 GMT 2023

PRIMARY

INN

10486

Created by admin on Sat Dec 16 16:42:30 GMT 2023 , Edited by admin on Sat Dec 16 16:42:30 GMT 2023

PRIMARY

FDA UNII

51FM0REX6F

Created by admin on Sat Dec 16 16:42:30 GMT 2023 , Edited by admin on Sat Dec 16 16:42:30 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methyl-Ribose	1_1-1_25	25 / 25

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_25	24 / 24

Related Record Type Details


					51FM0REX6F

ACTIVE MOIETY

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_5] [1_6] [1_8] [1_9] [1_13] [1_25]		CYTOSINE		5-METHYLCYTOSINE	6R795CQT4H

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL