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Details

Stereochemistry ACHIRAL
Molecular Formula C21H21O4P
Molecular Weight 368.3628
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRI-P-CRESYL PHOSPHATE

SMILES

CC1=CC=C(OP(=O)(OC2=CC=C(C)C=C2)OC3=CC=C(C)C=C3)C=C1

InChI

InChIKey=BOSMZFBHAYFUBJ-UHFFFAOYSA-N
InChI=1S/C21H21O4P/c1-16-4-10-19(11-5-16)23-26(22,24-20-12-6-17(2)7-13-20)25-21-14-8-18(3)9-15-21/h4-15H,1-3H3

HIDE SMILES / InChI

Molecular Formula C21H21O4P
Molecular Weight 368.3628
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Tri-p-cresyl phosphate is a nonneurotoxic regioisomer of tri-o-cresyl phosphate and a congener of tri-p-ethylphenyl phosphate. Patch tests (triphenyl phosphate allergy) with analytical grade triphenyl phosphate, tri-m-cresyl phosphate, and tri-p-cresyl phosphate in the concentrations 5%, 0.5% and 0.05% pet. showed positive reactions to 0.05% triphenyl phosphate and 0.5% tri-m-cresyl phosphate, but no reaction to tri-p-cresyl phosphate.

Approval Year

PubMed

PubMed

TitleDatePubMed
Preparation of microcapsules containing rare-earth metal elements.
2001 Jan-Feb
Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons.
2011 Sep 1
Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.
2012 Jun 15
Potential estrogenic effects of phosphorus-containing flame retardants.
2014 Jun 17
Affinities of organophosphate flame retardants to tumor suppressor gene p53: an integrated in vitro and in silico study.
2015 Jan 22
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:38:32 GMT 2025
Edited
by admin
on Mon Mar 31 22:38:32 GMT 2025
Record UNII
5149JKD098
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-2181
Preferred Name English
TRI-P-CRESYL PHOSPHATE
HSDB  
Common Name English
TRIS(P-METHYLPHENYL) PHOSPHATE
Common Name English
TRI-P-TOLYL PHOSPHATE
Common Name English
PHOSPHORIC ACID, TRI-P-TOLYL ESTER
Systematic Name English
P-TOLYL PHOSPHATE (C7H7O)3PO
Common Name English
TRIS(P-CRESYL) PHOSPHATE
Common Name English
TPC
Common Name English
PHOSPHORIC ACID, TRIS(4-METHYLPHENYL) ESTER
Systematic Name English
PHOSPHORIC ACID, TRI(4-TOLYL)ESTER
Systematic Name English
TRI-P-CRESYL PHOSPHATE [HSDB]
Common Name English
TRIS(4-METHYLPHENYL) PHOSPHATE
Systematic Name English
Code System Code Type Description
CAS
78-32-0
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY
PUBCHEM
6529
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY
ECHA (EC/EINECS)
201-105-6
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY
FDA UNII
5149JKD098
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY
NSC
2181
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY
EPA CompTox
DTXSID5052676
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY
HSDB
2559
Created by admin on Mon Mar 31 22:38:32 GMT 2025 , Edited by admin on Mon Mar 31 22:38:32 GMT 2025
PRIMARY