U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
(+)-cis-Permethrin is the active isomer of the insecticide permethrin. Topical formulations of permethrin (a mixture of isomers) are used for the treatment of lice infestations and scabeis. (+)-cis-Permethrin prolongs the activation of sodium channels in parasites and disrupts the function of neurons, leading to paralysis and death of the insects.

Originator

Curator's Comment: Permethrin was allegedly developed by US military to protect soldiers from insects in the jungle. (https://www.oammagazine.com/wp-content/uploads/2016/04/Treating%20your%20Clothes%20with%20Permethrin.pdf).

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
ELIMITE

Approved Use

ELIMITE (permethrin) 5% Cream is indicated for the treatment of infestation with Sarcoptesscabiei (scabies).

Launch Date

6.2000641E11
Curative
NIX

Approved Use

To treat head lice.

Launch Date

6.3391682E11
Curative
NIX

Approved Use

A synthetic pyrethrin derivative; like natural pyrethrins, acts as a neurotoxin by depolarizing the nerve cell membrane. Disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in the exoskeletal respiratory muscles of susceptible arthropods, including lice and mites.

Launch Date

5.12611189E11
Curative
NIX

Approved Use

A synthetic pyrethrin derivative; like natural pyrethrins, acts as a neurotoxin by depolarizing the nerve cell membrane. Disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in the exoskeletal respiratory muscles of susceptible arthropods, including lice and mites.

Launch Date

5.12611189E11
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
49.46 μg/mL
460 mg/kg single, oral
dose: 460 mg/kg
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN plasma
Rattus norvegicus
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
0.6 μg/mL
10 mg/kg bw single, oral
dose: 10 mg/kg bw
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Gallus gallus domesticus
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
253 ng/mL
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
615 ng/mL
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
868 ng/mL
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
159 mg × h/L
46 mg/kg single, intravenous
dose: 46 mg/kg
route of administration: Intravenous
experiment type: SINGLE
co-administered:
PERMETHRIN plasma
Rattus norvegicus
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
965 mg × h/L
460 mg/kg single, oral
dose: 460 mg/kg
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN plasma
Rattus norvegicus
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
1.95 mg × h/L
10 mg/kg bw single, oral
dose: 10 mg/kg bw
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Gallus gallus domesticus
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
16.45 mg × h/L
10 mg/kg bw single, intravenous
dose: 10 mg/kg bw
route of administration: Intravenous
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Gallus gallus domesticus
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
2.73 μg × h/mL
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
6.26 μg × h/mL
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
8.67 h
46 mg/kg single, intravenous
dose: 46 mg/kg
route of administration: Intravenous
experiment type: SINGLE
co-administered:
PERMETHRIN plasma
Rattus norvegicus
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
12.37 h
460 mg/kg single, oral
dose: 460 mg/kg
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN plasma
Rattus norvegicus
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
5.54 h
10 mg/kg bw single, oral
dose: 10 mg/kg bw
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Gallus gallus domesticus
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
4.73 h
10 mg/kg bw single, intravenous
dose: 10 mg/kg bw
route of administration: Intravenous
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Gallus gallus domesticus
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
5.08 h
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
4.82 h
143 g single, oral
dose: 143 g
route of administration: Oral
experiment type: SINGLE
co-administered:
PERMETHRIN serum
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
Funbound

Funbound

ValueDoseCo-administeredAnalytePopulation
10%
PERMETHRIN plasma
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: UNKNOWN
food status: UNKNOWN
Doses

Doses

DosePopulationAdverse events​
1 % 1 times / day multiple, topical
Recommended
Dose: 1 %, 1 times / day
Route: topical
Route: multiple
Dose: 1 %, 1 times / day
Sources:
unhealthy, adult
Health Status: unhealthy
Condition: pediculosis
Age Group: adult
Sex: unknown
Sources:
Other AEs: Skin and subcutaneous conditions NEC...
Other AEs:
Skin and subcutaneous conditions NEC
Sources:
5 % 1 times / day multiple, topical
Recommended
Dose: 5 %, 1 times / day
Route: topical
Route: multiple
Dose: 5 %, 1 times / day
Sources:
unhealthy, adult
Health Status: unhealthy
Condition: scabies
Age Group: adult
Sex: unknown
Sources:
Other AEs: Dystonia...
200 ug/kg 1 times / day multiple, oral
Recommended
Dose: 200 ug/kg, 1 times / day
Route: oral
Route: multiple
Dose: 200 ug/kg, 1 times / day
Sources:
unhealthy, adult
Health Status: unhealthy
Condition: crusted scabies
Age Group: adult
Sex: unknown
Sources:
AEs

AEs

AESignificanceDosePopulation
Skin and subcutaneous conditions NEC
1 % 1 times / day multiple, topical
Recommended
Dose: 1 %, 1 times / day
Route: topical
Route: multiple
Dose: 1 %, 1 times / day
Sources:
unhealthy, adult
Health Status: unhealthy
Condition: pediculosis
Age Group: adult
Sex: unknown
Sources:
Dystonia
5 % 1 times / day multiple, topical
Recommended
Dose: 5 %, 1 times / day
Route: topical
Route: multiple
Dose: 5 %, 1 times / day
Sources:
unhealthy, adult
Health Status: unhealthy
Condition: scabies
Age Group: adult
Sex: unknown
Sources:
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG



Drug as perpetrator​Drug as victim
PubMed

PubMed

TitleDatePubMed
Purification and preliminary characterization of permethrinase from a pyrethroid-transforming strain of Bacillus cereus.
1993 Jul
Purification and characterization of trans-permethrin metabolizing microsomal esterases from workers of the eastern subterranean termite, Reticulitermes flavipes (Kollar).
2001 Apr 27
Simultaneous determination of chlorpyrifos, permethrin, and their metabolites in rat plasma and urine by high-performance liquid chromatography.
2001 May-Jun
A solid phase extraction reversed-phase HPLC method for the simultaneous determination of methoprene, permethrin and selected metabolites in rat plasma and urine.
2001 Nov
Simultaneous determination of malathion, permethrin, DEET (N,N-diethyl-m-toluamide), and their metabolites in rat plasma and urine using high performance liquid chromatography.
2001 Sep
Residential pesticide use during pregnancy among a cohort of urban minority women.
2002 May
Determination of pyrethrin and pyrethroid pesticides in urine and water matrixes by liquid chromatography with diode array detection.
2003 Nov-Dec
Determination of enantiomers of synthetic pyrethroids in water by solid phase microextraction - enantioselective gas chromatography.
2004 Feb 25
Microbial transformation of pyrethroid insecticides in aqueous and sediment phases.
2004 Jan
Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding.
2005 Feb
HER-2/neu and CD117 (c-kit) overexpression in patients with pesticide exposure and extensive stage small cell lung carcinoma (ESSCLC).
2005 Jun 9
Laboratory and scaled up evaluation of cis-permethrin applied as a new ultra low volume formulation against Aedes aegypti (Diptera: Culicidae).
2006 Jan
Method of analysis of a selected group of pyrethroids in soil samples using off-line flow-through extraction and on-column direct large-volume injection in reversed phase high performance liquid chromatography.
2006 Sep
Efficacy of permethrin cream and oral ivermectin in treatment of scabies.
2007 Oct
Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes.
2008
Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates.
2008 Dec
Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome.
2008 Dec 30
Induction of hepatic estrogen-responsive gene transcription by permethrin enantiomers in male adult zebrafish.
2008 Jun 23
Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer.
2008 Jun 27
Mitigation assessment of vegetated drainage ditches for collecting irrigation runoff in California.
2008 Mar-Apr
Neurobehavioral toxicology of pyrethroid insecticides in adult animals: a critical review.
2008 Mar-Apr
Transcriptional response of rat frontal cortex following acute in vivo exposure to the pyrethroid insecticides permethrin and deltamethrin.
2008 Nov 18
The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides.
2009
Design of a compressed air modulator to be used in comprehensive multidimensional gas chromatography and its application in the determination of pesticide residues in grapes.
2009 Apr 10
Effect of permethrin insecticide on rat polymorphonuclear neutrophils.
2009 Dec 10
In vitro metabolism of pyrethroid pesticides by rat and human hepatic microsomes and cytochrome p450 isoforms.
2009 Jan
Measuring pyrethroids in sediment pore water using matrix-solid phase microextraction.
2009 Jan
Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin.
2009 Jan 15
Enantioselective induction of estrogen-responsive gene expression by permethrin enantiomers in embryo-larval zebrafish.
2009 Mar
Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor.
2009 May 15
Comparative functional observational battery study of twelve commercial pyrethroid insecticides in male rats following acute oral exposure.
2009 Nov
Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México.
2009 Oct 13
Estrogenic pyrethroid pesticides regulate expression of estrogen receptor transcripts in mouse Sertoli cells differently from 17beta-estradiol.
2010
Estrogenic activities of two synthetic pyrethroids and their metabolites.
2010
Time-dependent integrity during storage of natural surface water samples for the trace analysis of pharmaceutical products, feminizing hormones and pesticides.
2010 Apr 19
Developmental neurotoxicity of pyrethroid insecticides in zebrafish embryos.
2010 Jan
In vitro dermal absorption of pyrethroid pesticides in human and rat skin.
2010 Jul
Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays.
2010 Jul
Distribution and determinants of pesticide mixtures in cord serum using principal component analysis.
2010 Jul 15
Circadian clock regulates response to pesticides in Drosophila via conserved Pdp1 pathway.
2010 Jun
Splice variant specific increase in Ca2+/calmodulin-dependent protein kinase 1-gamma mRNA expression in response to acute pyrethroid exposure.
2010 May-Jun
Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort.
2010 Nov
Stereoselective biotransformation of permethrin to estrogenic metabolites in fish.
2010 Oct 18
Fetal exposure to chlordane and permethrin mixtures in relation to inflammatory cytokines and birth outcomes.
2011 Feb 15
Early life permethrin insecticide treatment leads to heart damage in adult rats.
2011 Sep
Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids.
2011 Sep 14
Activation of a tunicate (Ciona intestinalis) xenobiotic receptor orthologue by both natural toxins and synthetic toxicants.
2012 Feb
Permethrin exposure during puberty has the potential to enantioselectively induce reproductive toxicity in mice.
2012 Jul
A metabonomic investigation of the effects of 60 days exposure of rats to two types of pyrethroid insecticides.
2013 Nov 25
Early life permethrin treatment leads to long-term cardiotoxicity.
2013 Oct
Patents

Sample Use Guides

Apply topically to hair and scalp as 1% lotion (cream rinse) or apply topically to skin as 5% cream.
Route of Administration: Topical
To study effect of permethrin on sodium channel currents antennal lobe neurons of honeybees were used. Membrane currents were measured in the whole-cell configuration using a patch-clamp amplifier. Patch-clamp pipettes were pulled from borosilicate glass capillaries on a vertical pipette puller and then sylgard-coated to minimize pipette capacitance. The resistance of the recording electrode filled with intracellular solution ranged between 3 and 5 MΩ in standard extracellular solution. The liquid junction potential (<3 mV) was not corrected. Microelectrode offset potential was nulled before seal formation. After gigaseal formation and before membrane patch rupture, the resting holding potential was established at −80 mV and the residual microelectrode capacitance was nulled with a fast analog compensation circuit available on the amplifier. In the whole cell configuration, capacitance and series resistance were maximally compensated for. Passive leak currents and residual linear capacitative currents were subtracted using a P/4 protocol. Current-voltage relationships were generated by step depolarizations to test potentials from −80 to +70 mV (10 mV increment) from −80 mV. To assess pyrethroid effects, a single stimulation protocol consisted of a 3 ms depolarization from a holding potential of −80 mV to −10 mV. Trains of repetitive depolarizations at 13 Hz were also used and consisted of ten short stimulations (3 ms to −10 mV) with an interpulse duration (time lapse between the initiation of two successive pulses) of 78 ms. Permethrin was applied at a concentration of 10 uM.
Substance Class Mixture
Created
by admin
on Fri Jul 07 00:38:52 UTC 2023
Edited
by admin
on Fri Jul 07 00:38:52 UTC 2023
Record UNII
509F88P9SZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PERMETHRIN
HSDB   INCI   INN   ISO   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
USAN   INN   INCI  
Official Name English
Permethrin [WHO-DD]
Common Name English
PERMETHRIN [ISO]
Common Name English
permethrin [INN]
Common Name English
PERMETHRIN [JAN]
Common Name English
M-PHENOXYBENZYL (±)-3-(2,2-DICHLOROVINYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE
Systematic Name English
PERMETHRIN [HSDB]
Common Name English
MIXTURE OF CIS AND TRANS PERMETHRIN ISOMERS
Common Name English
PERMETHRIN [MI]
Common Name English
PERMETHRIN [VANDF]
Common Name English
CYCLOPROPANECARBOXYLIC ACID, 3-(2,2-DICHLOROETHENYL)-2,2-DIMETHYL-, (3-PHENOXYPHENYL)METHYL ESTER
Common Name English
PERMETHRIN [EMA EPAR VETERINARY]
Common Name English
PERMETHRIN [MART.]
Common Name English
PERMETHRIN COMPONENT OF VECTRA 3D
Brand Name English
(±)-3-PHENOXYBENZYL 3-(2,2-DICHLOROVINYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE
Systematic Name English
ELIMITE
Brand Name English
ACTIVYL TICK PLUS
Brand Name English
PERMETHRIN [INCI]
Common Name English
PERMETHRIN [IARC]
Common Name English
NSC-760105
Code English
PERMETHRIN [ORANGE BOOK]
Common Name English
COMPONENT OF ACTIVYL TICK PLUS
Common Name English
NIX
Brand Name English
ACTIVYL TICK PLUS COMPONENT PERMETHRIN
Common Name English
VECTRA 3D COMPONENT PERMETHRIN
Brand Name English
PERMETHRIN [USAN]
Common Name English
Classification Tree Code System Code
WHO-VATC QP53AC04
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
WHO-ATC P03AC04
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
WHO-ATC P03AC54
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 13.5
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
EMA VETERINARY ASSESSMENT REPORTS ACTIVYL TICK PLUS (AUTHORIZED)
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
NCI_THESAURUS C29727
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
NDF-RT N0000175847
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
NDF-RT N0000006014
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
EMA VETERINARY ASSESSMENT REPORTS VECTRA 3D [AUTHORIZED]
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
EPA PESTICIDE CODE 109701
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
Code System Code Type Description
DAILYMED
509F88P9SZ
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
PUBCHEM
40326
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
ALANWOOD
permethrin
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
FDA UNII
509F88P9SZ
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
NSC
760105
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
MESH
D026023
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
LACTMED
Permethrin
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
CHEBI
34911
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
SMS_ID
100000091844
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
EPA CompTox
DTXSID8022292
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
DRUG CENTRAL
4152
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
MERCK INDEX
M8564
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY Merck Index
NCI_THESAURUS
C29354
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
INN
5510
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
DRUG BANK
DB04930
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
WIKIPEDIA
PERMETHRIN
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
ChEMBL
CHEMBL1525
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
USAN
U-105
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
HSDB
6790
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
ECHA (EC/EINECS)
258-067-9
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
CAS
52645-53-1
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
EVMPD
SUB09734MIG
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY
RXCUI
33199
Created by admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
PRIMARY RxNorm
All of the following components must be present:
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
METABOLITE -> PARENT
METABOLITE -> PARENT
METABOLITE -> PARENT
METABOLITE -> PARENT
Related Record Type Details
ACTIVE MOIETY
Definition References