(+)-cis-Permethrin is the active isomer of the insecticide permethrin. Topical formulations of permethrin (a mixture of isomers) are used for the treatment of lice infestations and scabeis. (+)-cis-Permethrin prolongs the activation of sodium channels in parasites and disrupts the function of neurons, leading to paralysis and death of the insects.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2362985 |
|||
Target ID: CHEMBL2362984 |
|||
Target ID: CHEMBL2362985 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25390654 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Curative | ELIMITE Approved UseELIMITE (permethrin) 5% Cream is indicated for the treatment of infestation with Sarcoptesscabiei (scabies). Launch Date6.2000641E11 |
|||
Curative | NIX Approved UseTo treat head lice. Launch Date6.3391682E11 |
|||
Curative | NIX Approved UseA synthetic pyrethrin derivative; like natural pyrethrins, acts as a neurotoxin by depolarizing the nerve cell membrane. Disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in the exoskeletal respiratory muscles of susceptible arthropods, including lice and mites. Launch Date5.12611189E11 |
|||
Curative | NIX Approved UseA synthetic pyrethrin derivative; like natural pyrethrins, acts as a neurotoxin by depolarizing the nerve cell membrane. Disrupts the sodium channel current by which membrane repolarization is regulated resulting in fatal paralysis of the nerves in the exoskeletal respiratory muscles of susceptible arthropods, including lice and mites. Launch Date5.12611189E11 |
Cmax
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
49.46 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/1871768 |
460 mg/kg single, oral dose: 460 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
0.6 μg/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/26302029 |
10 mg/kg bw single, oral dose: 10 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Gallus gallus domesticus population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
253 ng/mL |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
615 ng/mL |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
868 ng/mL |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
AUC
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
159 mg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/1871768 |
46 mg/kg single, intravenous dose: 46 mg/kg route of administration: Intravenous experiment type: SINGLE co-administered: |
PERMETHRIN plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
965 mg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/1871768 |
460 mg/kg single, oral dose: 460 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
1.95 mg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/26302029 |
10 mg/kg bw single, oral dose: 10 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Gallus gallus domesticus population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
16.45 mg × h/L EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/26302029 |
10 mg/kg bw single, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
PERMETHRIN serum | Gallus gallus domesticus population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
2.73 μg × h/mL |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
6.26 μg × h/mL |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
T1/2
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
8.67 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/1871768 |
46 mg/kg single, intravenous dose: 46 mg/kg route of administration: Intravenous experiment type: SINGLE co-administered: |
PERMETHRIN plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
12.37 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/1871768 |
460 mg/kg single, oral dose: 460 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
5.54 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/26302029 |
10 mg/kg bw single, oral dose: 10 mg/kg bw route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Gallus gallus domesticus population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
4.73 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/26302029 |
10 mg/kg bw single, intravenous dose: 10 mg/kg bw route of administration: Intravenous experiment type: SINGLE co-administered: |
PERMETHRIN serum | Gallus gallus domesticus population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
5.08 h |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
|
4.82 h |
143 g single, oral dose: 143 g route of administration: Oral experiment type: SINGLE co-administered: |
PERMETHRIN serum | Homo sapiens population: UNHEALTHY age: ADULT sex: MALE food status: UNKNOWN |
Funbound
Value | Dose | Co-administered | Analyte | Population |
---|---|---|---|---|
10% EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31248885 |
PERMETHRIN plasma | Homo sapiens population: UNKNOWN age: UNKNOWN sex: UNKNOWN food status: UNKNOWN |
Doses
Dose | Population | Adverse events |
---|---|---|
1 % 1 times / day multiple, topical Recommended Dose: 1 %, 1 times / day Route: topical Route: multiple Dose: 1 %, 1 times / day Sources: |
unhealthy, adult Health Status: unhealthy Condition: pediculosis Age Group: adult Sex: unknown Sources: |
Other AEs: Skin and subcutaneous conditions NEC... |
5 % 1 times / day multiple, topical Recommended Dose: 5 %, 1 times / day Route: topical Route: multiple Dose: 5 %, 1 times / day Sources: |
unhealthy, adult Health Status: unhealthy Condition: scabies Age Group: adult Sex: unknown Sources: |
Other AEs: Dystonia... |
200 ug/kg 1 times / day multiple, oral Recommended Dose: 200 ug/kg, 1 times / day Route: oral Route: multiple Dose: 200 ug/kg, 1 times / day Sources: |
unhealthy, adult Health Status: unhealthy Condition: crusted scabies Age Group: adult Sex: unknown Sources: |
AEs
AE | Significance | Dose | Population |
---|---|---|---|
Skin and subcutaneous conditions NEC | 1 % 1 times / day multiple, topical Recommended Dose: 1 %, 1 times / day Route: topical Route: multiple Dose: 1 %, 1 times / day Sources: |
unhealthy, adult Health Status: unhealthy Condition: pediculosis Age Group: adult Sex: unknown Sources: |
|
Dystonia | 5 % 1 times / day multiple, topical Recommended Dose: 5 %, 1 times / day Route: topical Route: multiple Dose: 5 %, 1 times / day Sources: |
unhealthy, adult Health Status: unhealthy Condition: scabies Age Group: adult Sex: unknown Sources: |
Overview
CYP3A4 | CYP2C9 | CYP2D6 | hERG |
---|---|---|---|
OverviewOther
Other Inhibitor | Other Substrate | Other Inducer |
---|---|---|
Drug as perpetrator
Target | Modality | Activity | Metabolite | Clinical evidence |
---|---|---|---|---|
no | ||||
yes |
Drug as victim
Target | Modality | Activity | Metabolite | Clinical evidence |
---|---|---|---|---|
likely | ||||
likely | ||||
likely | ||||
likely | ||||
likely | ||||
no | ||||
no | ||||
no | ||||
no | ||||
yes [Km 2.8 uM] | ||||
yes | ||||
yes | ||||
yes | ||||
yes | ||||
yes |
PubMed
Title | Date | PubMed |
---|---|---|
Purification and preliminary characterization of permethrinase from a pyrethroid-transforming strain of Bacillus cereus. | 1993 Jul |
|
Purification and characterization of trans-permethrin metabolizing microsomal esterases from workers of the eastern subterranean termite, Reticulitermes flavipes (Kollar). | 2001 Apr 27 |
|
Simultaneous determination of chlorpyrifos, permethrin, and their metabolites in rat plasma and urine by high-performance liquid chromatography. | 2001 May-Jun |
|
A solid phase extraction reversed-phase HPLC method for the simultaneous determination of methoprene, permethrin and selected metabolites in rat plasma and urine. | 2001 Nov |
|
Simultaneous determination of malathion, permethrin, DEET (N,N-diethyl-m-toluamide), and their metabolites in rat plasma and urine using high performance liquid chromatography. | 2001 Sep |
|
Residential pesticide use during pregnancy among a cohort of urban minority women. | 2002 May |
|
Determination of pyrethrin and pyrethroid pesticides in urine and water matrixes by liquid chromatography with diode array detection. | 2003 Nov-Dec |
|
Determination of enantiomers of synthetic pyrethroids in water by solid phase microextraction - enantioselective gas chromatography. | 2004 Feb 25 |
|
Microbial transformation of pyrethroid insecticides in aqueous and sediment phases. | 2004 Jan |
|
Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. | 2005 Feb |
|
HER-2/neu and CD117 (c-kit) overexpression in patients with pesticide exposure and extensive stage small cell lung carcinoma (ESSCLC). | 2005 Jun 9 |
|
Laboratory and scaled up evaluation of cis-permethrin applied as a new ultra low volume formulation against Aedes aegypti (Diptera: Culicidae). | 2006 Jan |
|
Method of analysis of a selected group of pyrethroids in soil samples using off-line flow-through extraction and on-column direct large-volume injection in reversed phase high performance liquid chromatography. | 2006 Sep |
|
Efficacy of permethrin cream and oral ivermectin in treatment of scabies. | 2007 Oct |
|
Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. | 2008 |
|
Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates. | 2008 Dec |
|
Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome. | 2008 Dec 30 |
|
Induction of hepatic estrogen-responsive gene transcription by permethrin enantiomers in male adult zebrafish. | 2008 Jun 23 |
|
Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer. | 2008 Jun 27 |
|
Mitigation assessment of vegetated drainage ditches for collecting irrigation runoff in California. | 2008 Mar-Apr |
|
Neurobehavioral toxicology of pyrethroid insecticides in adult animals: a critical review. | 2008 Mar-Apr |
|
Transcriptional response of rat frontal cortex following acute in vivo exposure to the pyrethroid insecticides permethrin and deltamethrin. | 2008 Nov 18 |
|
The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides. | 2009 |
|
Design of a compressed air modulator to be used in comprehensive multidimensional gas chromatography and its application in the determination of pesticide residues in grapes. | 2009 Apr 10 |
|
Effect of permethrin insecticide on rat polymorphonuclear neutrophils. | 2009 Dec 10 |
|
In vitro metabolism of pyrethroid pesticides by rat and human hepatic microsomes and cytochrome p450 isoforms. | 2009 Jan |
|
Measuring pyrethroids in sediment pore water using matrix-solid phase microextraction. | 2009 Jan |
|
Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin. | 2009 Jan 15 |
|
Enantioselective induction of estrogen-responsive gene expression by permethrin enantiomers in embryo-larval zebrafish. | 2009 Mar |
|
Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptor. | 2009 May 15 |
|
Comparative functional observational battery study of twelve commercial pyrethroid insecticides in male rats following acute oral exposure. | 2009 Nov |
|
Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México. | 2009 Oct 13 |
|
Estrogenic pyrethroid pesticides regulate expression of estrogen receptor transcripts in mouse Sertoli cells differently from 17beta-estradiol. | 2010 |
|
Estrogenic activities of two synthetic pyrethroids and their metabolites. | 2010 |
|
Time-dependent integrity during storage of natural surface water samples for the trace analysis of pharmaceutical products, feminizing hormones and pesticides. | 2010 Apr 19 |
|
Developmental neurotoxicity of pyrethroid insecticides in zebrafish embryos. | 2010 Jan |
|
In vitro dermal absorption of pyrethroid pesticides in human and rat skin. | 2010 Jul |
|
Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays. | 2010 Jul |
|
Distribution and determinants of pesticide mixtures in cord serum using principal component analysis. | 2010 Jul 15 |
|
Circadian clock regulates response to pesticides in Drosophila via conserved Pdp1 pathway. | 2010 Jun |
|
Splice variant specific increase in Ca2+/calmodulin-dependent protein kinase 1-gamma mRNA expression in response to acute pyrethroid exposure. | 2010 May-Jun |
|
Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort. | 2010 Nov |
|
Stereoselective biotransformation of permethrin to estrogenic metabolites in fish. | 2010 Oct 18 |
|
Fetal exposure to chlordane and permethrin mixtures in relation to inflammatory cytokines and birth outcomes. | 2011 Feb 15 |
|
Early life permethrin insecticide treatment leads to heart damage in adult rats. | 2011 Sep |
|
Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids. | 2011 Sep 14 |
|
Activation of a tunicate (Ciona intestinalis) xenobiotic receptor orthologue by both natural toxins and synthetic toxicants. | 2012 Feb |
|
Permethrin exposure during puberty has the potential to enantioselectively induce reproductive toxicity in mice. | 2012 Jul |
|
A metabonomic investigation of the effects of 60 days exposure of rats to two types of pyrethroid insecticides. | 2013 Nov 25 |
|
Early life permethrin treatment leads to long-term cardiotoxicity. | 2013 Oct |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.drugs.com/monograph/permethrin.html
Apply topically to hair and scalp as 1% lotion (cream rinse) or apply topically to skin as 5% cream.
Route of Administration:
Topical
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/25390654
To study effect of permethrin on sodium channel currents antennal lobe neurons of honeybees were used. Membrane currents were measured in the whole-cell configuration using a patch-clamp amplifier. Patch-clamp pipettes were pulled from borosilicate glass capillaries on a vertical pipette puller and then sylgard-coated to minimize pipette capacitance. The resistance of the recording electrode filled with intracellular solution ranged between 3 and 5 MΩ in standard extracellular solution. The liquid junction potential (<3 mV) was not corrected. Microelectrode offset potential was nulled before seal formation. After gigaseal formation and before membrane patch rupture, the resting holding potential was established at −80 mV and the residual microelectrode capacitance was nulled with a fast analog compensation circuit available on the amplifier. In the whole cell configuration, capacitance and series resistance were maximally compensated for. Passive leak currents and residual linear capacitative currents were subtracted using a P/4 protocol. Current-voltage relationships were generated by step depolarizations to test potentials from −80 to +70 mV (10 mV increment) from −80 mV. To assess pyrethroid effects, a single stimulation protocol consisted of a 3 ms depolarization from a holding potential of −80 mV to −10 mV. Trains of repetitive depolarizations at 13 Hz were also used and consisted of ten short stimulations (3 ms to −10 mV) with an interpulse duration (time lapse between the initiation of two successive pulses) of 78 ms. Permethrin was applied at a concentration of 10 uM.
Substance Class |
Mixture
Created
by
admin
on
Edited
Fri Jul 07 00:38:52 UTC 2023
by
admin
on
Fri Jul 07 00:38:52 UTC 2023
|
Record UNII |
509F88P9SZ
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Brand Name | English | ||
|
Systematic Name | English | ||
|
Brand Name | English | ||
|
Brand Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Brand Name | English | ||
|
Common Name | English | ||
|
Brand Name | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
WHO-VATC |
QP53AC04
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
WHO-ATC |
P03AC04
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
WHO-ATC |
P03AC54
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
WHO-ESSENTIAL MEDICINES LIST |
13.5
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
EMA VETERINARY ASSESSMENT REPORTS |
ACTIVYL TICK PLUS (AUTHORIZED)
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
NCI_THESAURUS |
C29727
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
NDF-RT |
N0000175847
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
NDF-RT |
N0000006014
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
EMA VETERINARY ASSESSMENT REPORTS |
VECTRA 3D [AUTHORIZED]
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
||
|
EPA PESTICIDE CODE |
109701
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
509F88P9SZ
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
40326
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
permethrin
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
509F88P9SZ
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
760105
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
D026023
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
Permethrin
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
34911
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
100000091844
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
DTXSID8022292
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
4152
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
M8564
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | Merck Index | ||
|
C29354
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
5510
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
DB04930
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
PERMETHRIN
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
CHEMBL1525
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
U-105
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
6790
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
258-067-9
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
52645-53-1
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
SUB09734MIG
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | |||
|
33199
Created by
admin on Fri Jul 07 00:38:53 UTC 2023 , Edited by admin on Fri Jul 07 00:38:53 UTC 2023
|
PRIMARY | RxNorm |
All of the following components must be present:
Related Record | Type | Details | ||
---|---|---|---|---|
|
TARGET -> INHIBITOR |
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
METABOLITE -> PARENT |
|
||
|
METABOLITE -> PARENT |
|
||
|
METABOLITE -> PARENT |
|
||
|
METABOLITE -> PARENT |
|
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |
|