U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry MIXED
Molecular Formula C72H26O7S
Molecular Weight 1035.038
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARBON BLACK

SMILES

OC(=O)C1=CC2=C3C4=C5C6=C7C8=C(C=CC9=C8C%10=C(OC%11=CC%12=C%13C%14=C%15C%16C%17C(=C5C%18=C7C%10=C%11C%13=C%16%18)C3=C%19C(=CC%20=C%21C%22=C(C=C%23OCC%24=CC%25=C(C%14C%26C(CCSC%12%26)C%25)C%27=C%15C(C%17=C%19%21)=C%22C%23=C%24%27)C(=O)C%20=O)C2=O)C=C9)C=C6C=C14

InChI

InChIKey=ZBGANAZYHMVKTA-UHFFFAOYSA-N
InChI=1S/C72H26O7S/c73-68-24-11-23(72(76)77)22-10-20-7-17-2-1-16-3-4-29-44-32(16)33(17)47-35(20)50-38(22)39(24)51-42-25(68)12-26-40-41-27(70(75)69(26)74)13-30-45-36-21(15-78-30)9-19-8-18-5-6-80-71-28-14-31(79-29)46-54-43(28)55-49(37(18)71)34(19)48(36)58-62(53(41)45)61(52(40)42)66-60(51)59(50)65(57(47)56(44)46)63(54)67(66)64(55)58/h1-4,7,9-14,18,37,49,66-67,71H,5-6,8,15H2,(H,76,77)

HIDE SMILES / InChI

Molecular Formula C72H26O7S
Molecular Weight 1035.038
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

D&C Black #2 is the name, given by the FDA, for a highly pure form of carbon black prepared by combusting aromatic petroleum oil in the "oil furnace" process. It consists, essentially, of pure carbon. The Cosmetic, Toiletries and Fragrance Association (CTFA) petitioned the U.S. Food and Drug Administration (FDA) for approval to use carbon black in cosmetic formulations. The FDA granted approval on August 29, 2004, and now D&C Black #2 is used in all cosmetic products: mascaras, eyeliners, brush-on-brow, eyeshadows, and lipsticks.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study.
2016-03
Dysfunction of methionine sulfoxide reductases to repair damaged proteins by nickel nanoparticles.
2015-07-05
Graphene quantum dots induce apoptosis, autophagy, and inflammatory response via p38 mitogen-activated protein kinase and nuclear factor-κB mediated signaling pathways in activated THP-1 macrophages.
2015-01-02
Investigation of the effects of short-term inhalation of carbon nanoparticles on brains and lungs of c57bl/6j and p47(phox-/-) mice.
2014-07
Exposure-response estimates for diesel engine exhaust and lung cancer mortality based on data from three occupational cohorts.
2014-02
Traffic-related air pollution exposure in the first year of life and behavioral scores at 7 years of age.
2013-06
Carbon particles in airway macrophage as a surrogate marker in the early detection of lung diseases.
2012-04
Cytotoxicity evaluation of oxidized single-walled carbon nanotubes and graphene oxide on human hepatoma HepG2 cells: an iTRAQ-coupled 2D LC-MS/MS proteome analysis.
2012-03
Time-series analysis of mortality effects of fine particulate matter components in Detroit and Seattle.
2011-04
Effect modification of air pollution on Urinary 8-Hydroxy-2'-Deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions.
2010-12-07
Vascular effects of ultrafine particles in persons with type 2 diabetes.
2010-12
Effect of engineered nanoparticles on vasomotor responses in rat intrapulmonary artery.
2010-06-01
Toxicogenomics of water chemistry influence on chronic lead exposure to the fathead minnow (Pimephales promelas).
2008-05-01
A comparison of proximity and land use regression traffic exposure models and wheezing in infants.
2007-02
Determination of mercury in carbon black by cold vapor atomic absorption spectrometry.
2006-03-04
Inhalation toxicology of urban ambient particulate matter: acute cardiovascular effects in rats.
2001-10
Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture.
2001-06
Prolonged cataleptogenic effects of potentized homoeopathic drugs.
1986

Sample Use Guides

Mascaras, eyeliners, brush-on-brow, eye shadows, lipsticks, blushers & foundations
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:03:46 GMT 2025
Edited
by admin
on Mon Mar 31 18:03:46 GMT 2025
Record UNII
4XYU5U00C4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BLACK 2
INCI  
INCI  
Preferred Name English
CARBON BLACK
HSDB   INCI  
INCI  
Official Name English
CI 77266
INCI  
INCI  
Preferred Name English
LAMPBLACK
Common Name English
D&C BLACK NO. 2
II  
Common Name English
UNIPURE BLACK LC 902 GRAN
Brand Name English
C.I. 77266
Common Name English
DC BLACK NO. 2
Common Name English
VEGETABLE CARBON [MART.]
Common Name English
CARBONEUM [HPUS]
Common Name English
VEGETABLE CARBON (E 153)
Common Name English
C.I. PIGMENT BLACK 7
Common Name English
CARBON BLACK [IARC]
Common Name English
D&C BLACK NO. 2 [II]
Common Name English
C.I. PIGMENT BLACK 6
Common Name English
UNIPURE BLACK LC 902
Brand Name English
CARBON BLACK [HSDB]
Common Name English
CARBONEUM
HPUS  
Common Name English
Classification Tree Code System Code
CFR 21 CFR 178.3297
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
NCI_THESAURUS C461
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
CFR 21 CFR 176.170
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
Food Contact Sustance Notif, (FCN No.) FCN NO. 1088
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
Code System Code Type Description
EPA CompTox
DTXSID7051216
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
EVMPD
SUB21258
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
ECHA (EC/EINECS)
215-609-9
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
RXCUI
2032
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY RxNorm
DAILYMED
4XYU5U00C4
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
PUBCHEM
5462310
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
WIKIPEDIA
Carbon black
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
SMS_ID
100000088369
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
DRUG BANK
DB11980
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
CAS
1333-86-4
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
FDA UNII
4XYU5U00C4
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
HSDB
953
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY
NCI_THESAURUS
C77511
Created by admin on Mon Mar 31 18:03:46 GMT 2025 , Edited by admin on Mon Mar 31 18:03:46 GMT 2025
PRIMARY