U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2023
446
Substance Class Protein
Created
by admin
on Wed Apr 02 02:53:41 GMT 2025
Edited
by admin
on Wed Apr 02 02:53:41 GMT 2025
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
4W3KFI3TN3
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
Talquetamab
INN   USAN  
Official Name English
JNJ-64407564
Preferred Name English
Talquetamab [WHO-DD]
Common Name English
Immunoglobulin G4 [233-proline,239-alanine,240-alanine,410-leucine,414-lysine], anti-(human CD3 antigen) (human monoclonal JNJ-63483043 ?4-chain), disulfide with human monoclonal JNJ-63483043 ?-chain, (231?224?), (234?227?)-bis(disulfide) with immunoglob
Common Name English
talquetamab [INN]
Common Name English
Immunoglobulin G4-kappa/G4-lambda, anti-[Homo sapiens GPRC5D (G protein-coupled receptor class C group 5 member D)], and anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4)], humanized and chimeric monoclonal antibody; bispecific gamma4 heavy chain humanized an
Common Name English
TALQUETAMAB [USAN]
Common Name English
IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 814921
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
Code System Code Type Description
DAILYMED
4W3KFI3TN3
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
FDA UNII
4W3KFI3TN3
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
USAN
JK-141
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
CAS
2226212-40-2
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
SMS_ID
300000010796
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
INN
11173
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
NCI_THESAURUS
C171840
Created by admin on Wed Apr 02 02:53:41 GMT 2025 , Edited by admin on Wed Apr 02 02:53:41 GMT 2025
PRIMARY
From To
1_22 1_98
1_139 3_214
1_152 1_208
1_231 2_224
1_234 2_227
1_266 1_326
1_372 1_430
2_22 2_96
2_132 4_214
2_145 2_201
2_259 2_319
2_365 2_423
3_22 3_90
3_137 3_196
4_23 4_88
4_134 4_194
Related Record Type Details
Talquetamab-TGVS
SUB_CONCEPT->SUBSTANCE
T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN
TARGET -> ACTIVATOR
G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER D
TARGET->LIGAND
CD3
CD3
TARGET -> ACTIVATOR
Related Record Type Details
Talquetamab
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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