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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H28N2O2
Molecular Weight 340.4592
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ETHYLHYDROCUPREINE

SMILES

[H][C@]1(C[C@@H]2CC[N@]1C[C@@H]2CC)[C@H](O)C3=C4C=C(OCC)C=CC4=NC=C3

InChI

InChIKey=SUWZHLCNFQWNPE-LATRNWQMSA-N
InChI=1S/C21H28N2O2/c1-3-14-13-23-10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-4-2)12-18(17)19/h5-7,9,12,14-15,20-21,24H,3-4,8,10-11,13H2,1-2H3/t14-,15-,20-,21+/m0/s1

HIDE SMILES / InChI

Molecular Formula C21H28N2O2
Molecular Weight 340.4592
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Ethylhydrocupreine Hydrochloride (optochin) is a reagent used in the alteration in bacterial morphology, it is now used in cell culture techniques for the presumptive identification of Streptococcus pneumoniae, which is optochin-sensitive, from other alpha-hemolytic streptococci such as viridans streptococci, which are resistant. However, a single standardized procedure does not exist. Optochin is included neither in the current EUCAST breakpoint tables nor in the CLSI performance standards for antimicrobial susceptibility testing.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
in mice: The ethylhydrocuprein (optochin base) was administered in the form of a 2 per cent solution in olive oil, given under the skin of the back. This treatment was given, in the first instance, immediately after the infection; if a second dose was given it was given after an interval of 24 hours
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
4W030VS2OG
Record Status Validated (UNII)
Record Version