5-(TRIFLUOROMETHYL)URACIL

FC(F)(F)C1=CNC(=O)NC1=O

InChIKey=LMNPKIOZMGYQIU-UHFFFAOYSA-N

InChI=1S/C5H3F3N2O2/c6-5(7,8)2-1-9-4(12)10-3(2)11/h1H,(H2,9,10,11,12)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Simple and rapid enzymatic method for the synthesis of single-strand oligonucleotides containing trifluorothymidine.	2010-11	21128175
The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4'-benzamido-2'-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations.	2010-09-01	20696582
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation.	2005-01-03	15582458
Synthesis and herbicidal activity of novel heterocyclic protoporphyrinogen oxidase inhibitors.	2004-12	15578598
Synthesis and in vitro activity of D- and L-enantiomers of 5-(trifluoromethyl)uracil nucleoside derivatives.	2001-09-21	11562969
Influence of radiation sterilization on the stability of trifluorothymidine.	2001-07-17	11427351
Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.	1994-08-17	8080452

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:25:25 GMT 2025` Edited by `admin` on `Mon Mar 31 21:25:25 GMT 2025`
Record UNII	4U846R5P34
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-(TRIFLUOROMETHYL)URACIL

Systematic Name

English

NSC-73757

Preferred Name

English

URACIL, 5-(TRIFLUOROMETHYL)-

Systematic Name

English

2,4(1H,3H)-PYRIMIDINEDIONE, 5-(TRIFLUOROMETHYL)-

Systematic Name

English

5-(TRIFLUOROMETHYL)-2,4(1H,3H)-PYRIMIDINEDIONE

Systematic Name

English

5-(TRIFLUOROMETHYL)PYRIMIDINE-2,4-DIOL

Systematic Name

English

TRIFLUOROTHYMINE

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

200-197-5