Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C13H20N2O3S.ClH |
Molecular Weight | 320.835 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCOC(=O)\C=C1/S[C@H](N2CCCCC2)C(=O)N1C
InChI
InChIKey=AOHAFCXGDWOODX-WCXPBQLDSA-N
InChI=1S/C13H20N2O3S.ClH/c1-3-18-11(16)9-10-14(2)12(17)13(19-10)15-7-5-4-6-8-15;/h9,13H,3-8H2,1-2H3;1H/b10-9-;/t13-;/m0./s1
Molecular Formula | C13H20N2O3S |
Molecular Weight | 284.374 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 1 |
Optical Activity | UNSPECIFIED |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Dexetozoline is a safe and effective diuretic agent in the treatment of acute cardiac failure. In isolated rings of guinea-pig aorta not responding to acetylcholine, the diuretic dexetozoline did not influence basal vascular tone but inhibited noradrenaline- and histamine-induced contractions. Dexetozoline has a very high bioavailability after oral administration and is fairly lipohilic. The half-life of etozolin is 2.5 h. Dexetozoline accumulates in cirrhosis.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1766576
Mean daily dose 666 mg for 7 days
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:54:02 GMT 2023
by
admin
on
Sat Dec 16 01:54:02 GMT 2023
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Record UNII |
4S661NBY7C
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Record Status |
Validated (UNII)
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Record Version |
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-
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4S661NBY7C
Created by
admin on Sat Dec 16 01:54:02 GMT 2023 , Edited by admin on Sat Dec 16 01:54:02 GMT 2023
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76972808
Created by
admin on Sat Dec 16 01:54:02 GMT 2023 , Edited by admin on Sat Dec 16 01:54:02 GMT 2023
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Related Record | Type | Details | ||
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RACEMATE -> ENANTIOMER |