Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C13H20N2O3S.ClH |
| Molecular Weight | 320.835 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCOC(=O)\C=C1/S[C@H](N2CCCCC2)C(=O)N1C
InChI
InChIKey=AOHAFCXGDWOODX-WCXPBQLDSA-N
InChI=1S/C13H20N2O3S.ClH/c1-3-18-11(16)9-10-14(2)12(17)13(19-10)15-7-5-4-6-8-15;/h9,13H,3-8H2,1-2H3;1H/b10-9-;/t13-;/m0./s1
| Molecular Formula | C13H20N2O3S |
| Molecular Weight | 284.374 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Dexetozoline is a safe and effective diuretic agent in the treatment of acute cardiac failure. In isolated rings of guinea-pig aorta not responding to acetylcholine, the diuretic dexetozoline did not influence basal vascular tone but inhibited noradrenaline- and histamine-induced contractions. Dexetozoline has a very high bioavailability after oral administration and is fairly lipohilic. The half-life of etozolin is 2.5 h. Dexetozoline accumulates in cirrhosis.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1766576
Mean daily dose 666 mg for 7 days
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:03:17 GMT 2025
by
admin
on
Mon Mar 31 21:03:17 GMT 2025
|
| Record UNII |
4S661NBY7C
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
4S661NBY7C
Created by
admin on Mon Mar 31 21:03:17 GMT 2025 , Edited by admin on Mon Mar 31 21:03:17 GMT 2025
|
PRIMARY | |||
|
76972808
Created by
admin on Mon Mar 31 21:03:17 GMT 2025 , Edited by admin on Mon Mar 31 21:03:17 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
RACEMATE -> ENANTIOMER |