Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C17H14N2O4 |
Molecular Weight | 310.3041 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(=O)C2=CC=CC=C2NC(=O)[C@]13O[C@@H]3C4=CC(O)=CC=C4
InChI
InChIKey=BDDNYDPRCCDQQJ-PBHICJAKSA-N
InChI=1S/C17H14N2O4/c1-19-15(21)12-7-2-3-8-13(12)18-16(22)17(19)14(23-17)10-5-4-6-11(20)9-10/h2-9,14,20H,1H3,(H,18,22)/t14-,17+/m1/s1
Molecular Formula | C17H14N2O4 |
Molecular Weight | 310.3041 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/11916664Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/23770564 | https://www.ncbi.nlm.nih.gov/pubmed/24773150 | https://www.ncbi.nlm.nih.gov/pubmed/5823102
Sources: https://www.ncbi.nlm.nih.gov/pubmed/11916664
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/23770564 | https://www.ncbi.nlm.nih.gov/pubmed/24773150 | https://www.ncbi.nlm.nih.gov/pubmed/5823102
Cyclopenol is naturally occurring 7-membered 2,5-dioxopiperazine alkaloid isolated from the extract of fungus Penicillium cyclopium , Penicillium sclerotiorum etc. Cyclopenol can be converted into the quinolone viridicatol, by the enzyme cyclopenase present in the conidia. Cyclopenol have phytotoxic and antimicrobial activities.
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL335 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23770564 |
20.0 µM [IC50] |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
PubMed
Title | Date | PubMed |
---|---|---|
STUDIES IN THE BIOCHEMISTRY OF MICRO-ORGANISMS. 114. VIRIDICATOL AND CYCLOPENOL, METABOLITES OF PENICILLIUM VIRIDICATUM WESTLING AND PENICILLIUM CYCLOPIUM WESTLING. | 1963 Nov |
|
[On the synthesis of quinoline alkaloids in plants. 2. Fermentativ conversion of the penicillin alkaloids cyclopenin and cyclopenol to viridicatin and viridicatol]. | 1967 Jul |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:52:59 GMT 2023
by
admin
on
Sat Dec 16 09:52:59 GMT 2023
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Record UNII |
4Q2498L80A
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Record Status |
Validated (UNII)
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Record Version |
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