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Details

Stereochemistry ACHIRAL
Molecular Formula C2O4.Ca.H2O
Molecular Weight 146.112
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CALCIUM OXALATE MONOHYDRATE

SMILES

O.[Ca++].[O-]C(=O)C([O-])=O

InChI

InChIKey=LQHWSGSWNOHVHO-UHFFFAOYSA-L
InChI=1S/C2H2O4.Ca.H2O/c3-1(4)2(5)6;;/h(H,3,4)(H,5,6);;1H2/q;+2;/p-2

HIDE SMILES / InChI

Molecular Formula C2HO4
Molecular Weight 89.0269
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Most of the kidney stones are composed of calcium phosphate and calcium oxalate, which enter into the body through diet. Both sources of oxalates become dangerous when normal flora of gastrointestinal tract is disturbed. Several genetic disorders inducing hypercalciuria and hyperoxaluria were found to be associated with the formation of calcium oxalate stones. Calcium oxalate stones are caused by too much oxalate in the urine. Oxalobacter and Lactobacillus species exist symbiotically in the human gut and prevent stone formation by altering some biochemical pathways through the production of specific enzymes that help in the degradation of oxalate salts. Unfortunately, modern medical practice influences on O. formigenes colonization and the amount of these bacterias progressively come down and as a result the rising incidence of kidney stones. Recent experiments have shown the efficacy of the two medicinal and aromatic plants: Ammi visnaga and Punica granatum against the crystallization of calcium oxalate. The prevention and treatment of urinary lithiasis by plants remains an alternative for medical methods.

Approval Year

PubMed

Substance Class Chemical
Record UNII
4PP86KK527
Record Status Validated (UNII)
Record Version