Details
Stereochemistry | UNKNOWN |
Molecular Formula | C9H14N4O |
Molecular Weight | 194.2337 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(N1CC1C#N)N2CC2C(N)=O
InChI
InChIKey=RPZOFMHRRHHDPZ-UHFFFAOYSA-N
InChI=1S/C9H14N4O/c1-9(2,12-4-6(12)3-10)13-5-7(13)8(11)14/h6-7H,4-5H2,1-2H3,(H2,11,14)
Molecular Formula | C9H14N4O |
Molecular Weight | 194.2337 |
Charge | 0 |
Count |
|
Stereochemistry | MIXED |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Azimexon, a synthetic derivative of the 2-cyanaziridines, possesses the immunorestorative properties that were shown for patients with acquired immunodeficiency syndrome. Besides, azimexon had a role in managing cancer-associated dysregulation of the immune response. It was studied in clinical trials phase I to determine the drug's tolerable dose, toxicity, and effects on immune and nonimmune host defense parameters.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Animal experiments on the compensation of the immunosuppressive action of cyclophosphamide by 2-[-2-cyanaziridinyl-(1)-]-2-[-2-carbamoylaziridinyl-(1)]-propane BM 12 531. | 1978 |
|
Modulation in vitro of immune parameters in homosexual males with the preclinical complex of symptoms related to acquired immune deficiency syndrome by azimexon. | 1986 Jun |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2874196
Azimexon was given intravenously daily for 5 days to 19 cancer patients in a Phase I trial
Route of Administration:
Intravenous
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:14:52 GMT 2023
by
admin
on
Sat Dec 16 17:14:52 GMT 2023
|
Record UNII |
4NJ842U6BZ
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Code | English | ||
|
Code | English | ||
|
Common Name | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NCI_THESAURUS |
C797
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
||
|
NCI_THESAURUS |
C2139
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
||
|
NCI_THESAURUS |
C2080
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
C1347
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
264-679-7
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
CHEMBL149579
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
4NJ842U6BZ
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
4546
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
SUB05656MIG
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
DTXSID60867055
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
47294
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
64118-86-1
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
100000086084
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY | |||
|
C016866
Created by
admin on Sat Dec 16 17:14:52 GMT 2023 , Edited by admin on Sat Dec 16 17:14:52 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
---|---|---|---|---|
|
ACTIVE MOIETY |