Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H4NO2.Na |
| Molecular Weight | 145.0912 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[O-]C(=O)C1=CC=NC=C1
InChI
InChIKey=PVXCGWNPDFFPOV-UHFFFAOYSA-M
InChI=1S/C6H5NO2.Na/c8-6(9)5-1-3-7-4-2-5;/h1-4H,(H,8,9);/q;+1/p-1
| Molecular Formula | C6H4NO2 |
| Molecular Weight | 122.1015 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Isonicotinic acid considered to be inactive isomer of nicotinic acid. Isonicotinic acid is a metabolite of pyridine-4-carboxy hydrazide (isonicotinyl hydrazide; isoniazid) a front-line weapon in the battle against tuberculosis. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity. | 2008-04 |
|
| Linking two distinct layered networks of nanosized {Ln18} and {Cu24} wheels through isonicotinate ligands. | 2008 |
|
| Study on complex formation of biologically active pyridine derivatives with cyclodextrins by capillary electrophoresis. | 2007-11-30 |
|
| A series of lanthanide-transition metal frameworks based on 1-, 2-, and 3D metal-organic motifs linked by different 1D copper(I) halide motifs. | 2007-11-26 |
|
| Amine modification of digested peptide at C-terminal end during protein digestion by protease. | 2007-10 |
|
| Antimalarial cation-dimers synthesized in two steps from an inexpensive starting material, isonicotinic acid. | 2007-10 |
|
| Diversity of crystal structure with different lanthanide ions involving in situ oxidation-hydrolysis reaction. | 2007-09-28 |
|
| 3D homometallic carboxylate ferrimagnet constructed from a manganese(II) succinate carboxylate layer motif pillared by isonicotinate spacers. | 2007-09-03 |
|
| 3D coordination framework [Ln(4)(mu(3)-OH)(2)Cu(6)I(5)(IN)(8)(OAc)(3)] (IN = isonicotinate): employing 2D layers of lanthanide wheel clusters and 1D chains of copper halide clusters. | 2007-06-25 |
|
| A deliberate approach for the syntheses of heterometallic supramolecules containing dimolybdenum Mo(2)4+ species coordinated to other metal units. | 2007-06-14 |
|
| Surface modification of high-nuclearity lanthanide clusters: two tetramers constructed by cage-shaped [Dy26] clusters and isonicotinate linkers. | 2007-04-16 |
|
| On the relevance of an antiferromagnetic dimer model for the spin-gapped magnetic solids Cu(terpy)Mo2O7 and Cu(OH)(p-pyc)H2O. | 2007-04-02 |
|
| Identification of a cytochrome P450 cDNA (CYP98A5) from Phaseolus vulgaris, inducible by 3,5-dichlorosalicylic acid and 2,6-dichloro isonicotinic acid. | 2007-04 |
|
| A regenerable ruthenium tetraammine nitrosyl complex immobilized on a modified silica gel surface: preparation and studies of nitric oxide release and nitrite-to-NO conversion. | 2007-03-15 |
|
| Metallacrown-based compartments: selective encapsulation of three isonicotinate anions in non-centrosymmetric solids. | 2007-03-12 |
|
| LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method. | 2007-03-12 |
|
| First direct-formation and properties of microspherical superstructure. Morphology of diamineplatinum(II) complexes with isonicotinate. | 2007-02-07 |
|
| Photosensitizers containing the 1,8-naphthyridyl moiety and their use in dye-sensitized solar cells. | 2006-12-11 |
|
| Langerhans cells release prostaglandin D2 in response to nicotinic acid. | 2006-12 |
|
| A robust microporous 3D cobalt(II) coordination polymer with new magnetically frustrated 2D lattices: single-crystal transformation and guest modulation of cooperative magnetic properties. | 2006-11-28 |
|
| Spontaneously resolved homochiral 3D lanthanide-silver heterometallic coordination framework with extended helical Ln-O-Ag subunits. | 2006-11-13 |
|
| Coordination framework hosts consisting of 4-pyridyl-substituted carboxylic acid (PCA) dimers and 1D chains of Ni2+ and SCN-: a rational structural extension toward coordination framework hosts with large rectangular cavities. | 2006-11-13 |
|
| Comparison of the anti-neoplastic effects of dirhodium(II) tetrapropionate and its adducts with nicotinate and isonicotinate anions in mice bearing Ehrlich tumors. | 2006-10 |
|
| Accurate length control of supramolecular oligomerization: Vernier assemblies. | 2006-07-12 |
|
| Catalase-peroxidase of Mycobacterium bovis BCG converts isoniazid to isonicotinamide, but not to isonicotinic acid: differentiation parameter between enzymes of Mycobacterium bovis BCG and Mycobacterium tuberculosis. | 2006-05 |
|
| Effect of beclomethasone dipropionate and dexamethasone isonicotinate on lung function, bronchoalveolar lavage fluid cytology, and transcription factor expression in airways of horses with recurrent airway obstruction. | 2006-04-06 |
|
| First metal azide complex with isonicotinate as a bridging ligand showing new net topology: hydrothermal synthesis, structure, and magnetic properties. | 2006-04-03 |
|
| Monitoring the ingestion of anti-tuberculosis drugs by simple non-invasive methods. | 2006-01-13 |
|
| A rash imposition from a lifestyle omission: a case report of pellagra. | 2006-01 |
|
| Aerobic biodegradation of 4-methylpyridine and 4-ethylpyridine by newly isolated Pseudonocardia sp. strain M43. | 2006-01 |
|
| Synthesis, Biological, Spectral, and Thermal Investigations of Cobalt(II) and Nickel(II) Complexes of N-Isonicotinamido -2',4'-Dichlorobenzalaldimine. | 2006 |
|
| The role of serendipity in drug discovery. | 2006 |
|
| Isoniazid is not a lead compound for its pyridyl ring derivatives, isonicotinoyl amides, hydrazides, and hydrazones: a critical review. | 2006 |
|
| An investigation of the surface-enhanced Raman scattering (SERS) effect from a new substrate of silver-modified silver electrode. | 2005-12-15 |
|
| Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci. | 2005-10-06 |
|
| Open metal-organic framework containing cuprate chains. | 2005-09-05 |
|
| Determination of ethylene thiourea in urine by HPLC-DAD. | 2005-06-25 |
|
| Clinical presentation of abdominal tuberculosis in HIV seronegative adults. | 2005-06-21 |
|
| A solvothermally in situ generated mixed-ligand approach for NLO-active metal-organic framework materials. | 2005-06-13 |
|
| Surface-enhanced Raman spectroscopy using silver-coated porous glass-ceramic substrates. | 2005-06 |
|
| Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family. | 2005-05-15 |
|
| [Effects of a single dose of dexamethasone-21-isonicotinate on the phagocytosis performance of neutrophilic granulocytes and monocytes in periparturient dairy cows]. | 2005-04-05 |
|
| Synthesis and characterization of hydrogen-bonded assemblies of W6S8L6 clusters. | 2005-04-04 |
|
| Acetylation genotype and phenotype in patients with systemic lupus erythematosus. | 2005-03-24 |
|
| Ditopic redox-active polyferrocenyl zinc(II) dithiocarbamate macrocyclic receptors: synthesis, coordination and electrochemical recognition properties. | 2005-02-21 |
|
| A 3D coordination framework based on linkages of nanosized hydroxo lanthanide clusters and copper centers by isonicotinate ligands. | 2005-02-18 |
|
| A new layered zinc phosphate templated by protonated isonicotinate, [Zn2(C6H5NO2)2(HPO4)2]. | 2005-02 |
|
| Dinuclear zinc(II) dithiocarbamate macrocycles: ditopic receptors for a variety of guest molecules. | 2005-01-21 |
|
| Siloxane-supported organometallic compounds and their catalytic activities for the hydrosilylation of vinylsilanes and dienes. | 2005-01-07 |
|
| Antioxidant activity of new ruthenium compounds. | 2005 |
| Substance Class |
Chemical
Created
by
admin
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Edited
Mon Mar 31 19:54:58 GMT 2025
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on
Mon Mar 31 19:54:58 GMT 2025
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| Record UNII |
4N428DW41J
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| Record Status |
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| Record Version |
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