U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Jun 26 17:20:01 UTC 2021
Edited
by admin
on Sat Jun 26 17:20:01 UTC 2021
Source Materials Class ORGANISM
Source Materials Type AUTOLOGOUS HUMAN
Source Materials State LIVE ATTENUATED GENETICALLY MODIFIED
Source Materials Parent
Part BLOOD
Fraction Material Type CELLS
Fraction Name T CELL
Record UNII
4MD2J2T8SJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BREXUCABTAGENE AUTOLEUCEL
USAN  
Official Name English
BREXUCABTAGENE AUTOLEUCEL [USAN]
Common Name English
BREXUCABTAGENE AUTOLEUCEL [WHO-DD]
Common Name English
KTE-X19
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 515715
Created by admin on Sat Jun 26 17:20:01 UTC 2021 , Edited by admin on Sat Jun 26 17:20:01 UTC 2021
Code System Code Type Description
RXCUI
2387277
Created by admin on Sat Jun 26 17:20:01 UTC 2021 , Edited by admin on Sat Jun 26 17:20:01 UTC 2021
PRIMARY
FDA UNII
4MD2J2T8SJ
Created by admin on Sat Jun 26 17:20:01 UTC 2021 , Edited by admin on Sat Jun 26 17:20:01 UTC 2021
PRIMARY
NCI_THESAURUS
C170439
Created by admin on Sat Jun 26 17:20:01 UTC 2021 , Edited by admin on Sat Jun 26 17:20:01 UTC 2021
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CULTURE ACTIVATION (CD3/CD28 ANTIBODIES) IMMUNOLOGICAL
TRANSFECTION RETROVIRAL TRANSFECTION UNSPECIFIED SUBSTANCE 0f2235db
CD4-/CD8- ENRICHMENT CELL SEPARATION
T ENRICHMENT (Removal of impurities) CELL SEPARATION