DDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H8Cl4
Molecular Weight	318.025
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC(Cl)=C(C1=CC=C(Cl)C=C1)C2=CC=C(Cl)C=C2

InChI

InChIKey=UCNVFOCBFJOQAL-UHFFFAOYSA-N

InChI=1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H

HIDE SMILES / InChI

Molecular Formula	C14H8Cl4
Molecular Weight	318.025
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
DDT inhibits the functional activation of murine macrophages and decreases resistance to infection by Mycobacterium microti.	2002-06-05	12007859
[Effect of nonsteroidal estrogen-like substances on aromatase activity].	2002-05-31	12035542
Lack of antiandrogenic effects in adult male rats following acute exposure to 2,2-bis(4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE).	2002-05-24	11985884
Effects of furazolidone, PCB77, PCB126, Aroclor 1248, paraquat and p,p'-DDE on transketolase activity in embryonal chicken brain.	2002-05-01	11960673
Bioaccumulation of organochlorine contaminants in bowhead whales (Balaena mysticetus) from Barrow, Alaska.	2002-05	11994792
PCDDs/PCDFs, PCBs, and organochlorine pesticides in eggs of Eurasian sparrowhawks (Accipiter nisus), hobbies (Falco subbuteo), and northern goshawks (Accipiter gentilis) collected in the area of Berlin-Brandenburg, Germany.	2002-05	11994791
Effects of nonylphenol, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE), and pentachlorophenol on the adult female guinea pig reproductive tract.	2002-04-06	11934530
Intraspecific variation in trophic feeding levels and organochlorine concentrations in glaucous gulls (Larus hyperboreus) from Bjørnøya, the Barents Sea.	2002-04	11990768
Effects of contact time on the sequestration and bioavailability of different classes of hydrophobic organic chemicals to benthic oligochaetes (Tubificidae).	2002-04	11951948
Headspace solid-phase microextraction in combination with gas chromatography and tandem mass spectrometry for the determination of organochlorine and organophosphorus pesticides in whole numan blood.	2002-03-25	11936696
Residuals of beta-hexachlorocyclohexane, dichlorodiphenyltrichloroethane, and hexachlorobenzene in serum, and relations with consumption of dietary components in rural residents in Japan.	2002-03-08	11886087
Temporal trends of organochlorine pesticides in the Canadian Arctic atmosphere.	2002-03-01	11918008
The organochlorine pesticide residues and antioxidant enzyme activities in human breast tumors: is there any association?	2002-03	12038708
Levels of p,p'-DDE in liver of predatory birds from Calabria, Italy.	2002-03	11993812
Multiresidue determination of endosulfan and metabolic derivatives in human adipose tissue using automated liquid chromatographic cleanup and gas chromatographic analysis.	2002-03	11916021
Citrate-mediated increase in the uptake of weathered 2,2-bis(p-chlorophenyl) 1,1-dichloroethylene residues by plants.	2002-03	11878468
A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists.	2002-03	11861974
Exposure of juvenile guppies to three antiandrogens causes demasculinization and a reduced sperm count in adult males.	2002-03	11856573
Weight loss-induced rise in plasma pollutant is associated with reduced skeletal muscle oxidative capacity.	2002-03	11832359
Maternal serum level of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring.	2002-02-15	11836195
[Bioindication of organochlorine pesticides by night heron in Taihu wetland ecosystem].	2002-02	11993129
Fish consumption and plasma levels of organochlorines in a female population in Northern Norway.	2002-02	11871702
Heavy metals, HCB and p,p'-DDE in Ictalurus melas Raf. from Trasimeno and Corbara lakes, Italy.	2002-02	11815793
Exposures associated with serum organochlorine levels among postmenopausal women from western New York State.	2002-02	11813215
Reductive metabolism of p,p'-DDT and o,p'-DDT by rat liver cytochrome P450.	2002-02	11792678
Cord blood lymphocyte functions in newborns from a remote maritime population exposed to organochlorines and methylmercury.	2002-01-25	11820504
Residue levels of DDE and PCBs in the blood serum of women in the Port Said region of Egypt.	2002-01-04	11734345
Organochlorine and butyltin residues in walleye pollock (Theragra chalcogramma) from Bering Sea, Gulf of Alaska and Japan Sea.	2002-01	11833489
Meconium: a matrix reflecting potential fetal exposure to organochlorine pesticides and its metabolites.	2002-01	11800551
Organochlorine pesticide contamination in grassland-nesting passerines that breed in North America.	2002	11916037
Organochlorine accumulation and stable isotope ratios in an Atlantic salmon (Salmo salar) population from the Baltic Sea.	2001-12-17	11778947
Investigation of systemic lupus erythematosus in Nogales, Arizona.	2001-12-01	11724719
Persistent organochlorine residues and toxic evaluation of polychlorinated biphenyls in sharks from the Mediterranean Sea (Italy).	2001-12	11827119
Accumulation of DDT and mercury in prothonotary warblers (Protonotaria citrea) foraging in a heterogeneously contaminated environment.	2001-12	11764178
Variation of antioxidant enzyme activities of sprat (Sprattus sprattus) larvae and organic contaminant levels in mixed zooplankton from the southern North Sea.	2001-11	11763220
Increase in plasma pollutant levels in response to weight loss in humans is related to in vitro subcutaneous adipocyte basal lipolysis.	2001-11	11753575
Embryonic exposure to low-dose pesticides: effects on growth rate in the hatchling red-eared slider turtle.	2001-10-12	11594703
Antiandrogenic pesticides disrupt sexual characteristics in the adult male guppy Poecilia reticulata.	2001-10	11675272
Association of DDT with spontaneous abortion: a case-control study.	2001-10	11557181
Surfactant-enhanced solubilization and anaerobic biodegradation of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane (DDT) in contaminated soil.	2001-09-18	11558297
Solid-phase microextraction and gas chromatography-mass spectrometry analysis of p,p' -DDE in biological samples.	2001-09-15	11585136
Specific accumulation and elimination kinetics of tris(4-chlorophenyl)methane, tris(4-chlorophenyl)methanol, and other persistent organochlorines in humans from Japan.	2001-09	11673122
Determination of DDT and its metabolites in cattle dip soil available in aqueous phase after remediation.	2001-09	11599716
Plant-facilitated mobilization and translocation of weathered 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE) from an agricultural soil.	2001-09	11521833
Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila melanogaster B(II) cell in vitro assay.	2001-09	11521832
Analyses of lindane, vinclozolin, aldrin, p,p'-DDE, o,p'-DDT and p,p'-DDT in human serum using gas chromatography with electron capture detection and tandem mass spectrometry.	2001-08-25	11522051
Case-control study on concentrations of organohalogen compounds and titers of antibodies to Epstein-Barr virus antigens in the etiology of non-Hodgkin lymphoma.	2001-08	11697490
The association between local fish consumption and DDE, mirex, and HCB concentrations in the breast milk of Mohawk women at Akwesasne.	2001-06-28	11687911
Polybrominated diphenyl ethers in Swedish human liver and adipose tissue.	2001-05	11525501
Organochlorine pesticides in water, sediment, crops, and human fluids in a farming community in Ghana.	2001-05	11525500

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:36:15 GMT 2025` Edited by `admin` on `Mon Mar 31 17:36:15 GMT 2025`
Record UNII	4M7FS82U08
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-1153

Preferred Name

English

DDE	Locators: HSDB Sources:

Common Name

English

BENZENE, 1,1'-(2,2-DICHLOROETHENYLIDENE)BIS(4-CHLORO-

Systematic Name

English

DDE [HSDB]

Common Name

English

1,1'-(2,2-DICHLORO-1,1-ETHENEDIYL)BIS(4-CHLOROBENZENE)

Systematic Name

English

1,1'-(2,2-DICHLOROETHENE-1,1-DIYL)BIS(4-CHLOROBENZENE)

Systematic Name

English

1,1-DICHLORO-2,2-BIS(P-CHLOROPHENYL)ETHYLENE

Common Name

English

P,P'-DDE

Common Name

English

4,4'-DDE

Common Name

English

DDE, P,P'-

Common Name

English

Code System Code Type Description

HSDB

1625