Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:55:47 GMT 2023
by
admin
on
Sat Dec 16 13:55:47 GMT 2023
|
Protein Type | PEPTIDE |
Protein Sub Type | ANTI-APOPTOCTIC REGULATORY PROTEIN |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
4LUD924Y4D
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Record Status |
Validated (UNII)
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Record Version |
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-
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4LUD924Y4D
Created by
admin on Sat Dec 16 13:55:48 GMT 2023 , Edited by admin on Sat Dec 16 13:55:48 GMT 2023
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P98170
Created by
admin on Sat Dec 16 13:55:48 GMT 2023 , Edited by admin on Sat Dec 16 13:55:48 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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INHIBITOR -> TARGET |
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APG-1387 in combination with TNF-α potently decreased NPC cell viability by inducing apoptosis in majority of NPC cell lines. Eight human IAP proteins and Smac mimetics activate caspases by antagonizing XIAP, which directly inhibits key caspase.
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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