U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C10H8O3S.C4H11NO2
Molecular Weight 313.369
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIETHANOLAMINE NAPHTHALENE-2-SULFONATE

SMILES

OCCNCCO.OS(=O)(=O)C1=CC=C2C=CC=CC2=C1

InChI

InChIKey=MUYVPEZNWONMAN-UHFFFAOYSA-N
InChI=1S/C10H8O3S.C4H11NO2/c11-14(12,13)10-6-5-8-3-1-2-4-9(8)7-10;6-3-1-5-2-4-7/h1-7H,(H,11,12,13);5-7H,1-4H2

HIDE SMILES / InChI

Molecular Formula C4H11NO2
Molecular Weight 105.1356
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C10H8O3S
Molecular Weight 208.234
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sodium 2-naphthalenesulfonate is a sodium salt of naphthalene sulfonic acid. Sodium 2-naphthalenesulfonate is a surfactant-hydrotrope used in cosmetics. Use concentrations would be typically below 2%. In clinical studies, Sodium 2-naphthalenesulfonate was neither an irritant (tested up to 2%), cumulative irritant (tested up to 1%), nor a sensitizer (tested up to 1%). Sodium 2-naphthalenesulfonate is considered safe as used in cosmetic formulations intended to be applied to the skin.

Approval Year

PubMed

PubMed

TitleDatePubMed
Determination of cyclodextrins and their derivatives by capillary electrophoresis with indirect UV and conductivity detection.
2001 Apr
Determination of naphthalenesulfonic acid isomers by large-volume on-line derivatization and gas chromatography-mass spectrometry.
2001 Aug 17
Protonation effects on the inclusion complexation of 6-deoxy-6-diethylamino-beta-cyclodextrin with 2-anthracenesulfonate, 2-naphthalenesulfonate, 2,6-naphthalenedisulfonate, and 2,7-naphthalenedisulfonate in aqueous solutions.
2001 Jan
Binding affinity properties of dendritic glycosides based on a beta-cyclodextrin core toward guest molecules and concanavalin A.
2001 Nov 16
Investigation of naphtalene sulfonate compounds sorption in a soil artificially contaminated using batch and column assays.
2002
Stability study and determination of benzene- and naphthalenesulfonates following an on-line solid-phase extraction method using the new programmable field extraction system.
2002 Apr
Dendritic galactosides based on a beta-cyclodextrin core for the construction of site-specific molecular delivery systems: synthesis and molecular recognition studies.
2002 Feb 15
Development of generic liquid chromatography-mass spectrometry methods using experimental design.
2002 Jan
Isotachophoretic focusing and mass spectrometry detection as tools for improving the determination of aromatic sulfonates in capillary electrophoresis.
2002 Jul
Amplification of small analytes in polymer solution by capillary electrophoresis.
2002 Jun
Decomposition of 2-naphthalenesulfonate in aqueous solution by ozonation with UV radiation.
2002 Sep
Final report on the amended safety assessment of sodium polynaphthalenesulfonate and sodium naphthalenesulfonate.
2003
The determination of a potential impurity in Thalidomide drug substance and product by HPLC with indirect UV detection.
2003 Feb 5
Electrochemical synthesis of novel polypyrrole microstructures.
2003 Jan 21
Analysis of a retan agent used in the tanning process and its determination in tannery wastewater.
2003 Mar 15
Separation and migration behavior of positional and structural naphthalenesulfonate isomers by cyclodextrin-mediated capillary electrophoresis.
2004 Apr 9
Silver(I) arylsulfonates: a systematic study of "softer" hybrid inorganic-organic solids.
2004 Oct 18
Depolymerisation and biodegradation of a synthetic tanning agent by activated sludges, the bacteria Arthrobacter globiformis and Comamonas testosteroni, and the fungus Cunninghamella polymorpha.
2005 Aug
Decomposition of 2-naphthalenesulfonate in electroplating solution by ozonation with UV radiation.
2005 Feb 14
Biodegradation of naphthalene-2-sulfonic acid present in tannery wastewater by bacterial isolates Arthrobacter sp. 2AC and Comamonas sp. 4BC.
2005 Jun
Heterogeneity of the adsorption mechanism of low molecular weight compounds in reversed-phase liquid chromatography.
2006 Aug 15
Treatment of naphthalene-2-sulfonic acid from tannery wastewater by a granular activated carbon fixed bed inoculated with bacterial isolates Arthrobacter globiformis and Comamonas testosteroni.
2006 Feb
Measurement of monomolecular binding constants of neutral phenols into the beta-cyclodextrin by continuous frontal analysis in capillary and microchip electrophoresis via a competitive assay.
2006 Feb 3
A chromatographic estimate of the degree of surface heterogeneity of RPLC packing materials. III. Endcapped amido-embedded reversed phase.
2006 Jan 20
A chromatographic estimate of the degree of heterogeneity of RPLC packing materials. 1. Non-endcapped polymeric C30-bonded stationary phase.
2006 Jan 20
Nanostructuring of poly(diphenylamine) inside the galleries of montmorillonite organo clay through self-assembly approach.
2006 Jun
Adsorption mechanism in reversed-phase liquid chromatography. Effect of the surface coverage of a monomeric C18-silica stationary phase.
2006 May 19
The role of cross-linking structures to the formation of one-dimensional nano-organized polyaniline and their Raman fingerprint.
2008 Dec 1
trans-Diaqua-bis(ethyl-enediamine-κN,N')copper(II) bis[3-(3-pyrid-yl)propionate] dihydrate.
2008 Mar 5
Photochemical elimination of leaving groups from zwitterionic intermediates generated via electrocyclic ring closure of alpha,beta-unsaturated anilides.
2008 Nov 21
Efficient removal of aromatic sulfonates from wastewater by a recyclable polymer: 2-naphthalene sulfonate as a representative pollutant.
2008 Oct 1
Influence of anionic sulfonate-containing co-ligands on the solid structures of silver complexes supported by 4,4'-bipyridine bridges.
2008 Oct 21
Rich aggregate morphologies induced by organic salts in aqueous solutions of a cationic gemini surfactant with a short spacer.
2009 Dec 1
Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs.
2009 Jul 1
Experiments on moving interaction boundaries and their characteristics of focusing and probing of both guest and host target molecules.
2009 Sep 14
Preparation of poly(1,5 diamino naphthalene) nanobelts/nanodiscs through a "hard-soft combined templates" approach.
2010 Aug
The development of electrically conductive polycaprolactone fumarate-polypyrrole composite materials for nerve regeneration.
2010 Aug
Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile.
2010 Aug 19
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.
2010 Aug 24
Structure, morphology, and bioactivity of biocompatible systems derived from functionalized acrylic polymers based on 5-amino-2-naphthalene sulfonic acid.
2010 Jul 12
Microbial conversion of 5-sulfoisophthalic acid into 5-hydroxyisophthalic acid by Ochrobactrum anthropi S9.
2010 Mar
Patents

Sample Use Guides

In clinical studies, Sodium 2-naphthalenesulfonate was neither an irritant (tested up to 2%), cumulative irritant (tested up to 1%), nor a sensitizer (tested up to 1%).
Route of Administration: Topical
Substance Class Chemical
Created
by admin
on Sat Dec 16 12:18:29 GMT 2023
Edited
by admin
on Sat Dec 16 12:18:29 GMT 2023
Record UNII
4KQC35ZF1D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIETHANOLAMINE NAPHTHALENE-2-SULFONATE
Common Name English
ETHANOL, 2,2'-IMINOBIS-, 2-NAPHTHALENESULFONATE (SALT)
Common Name English
NAPHTHALENE-2-SULFONIC ACID, COMPOUND WITH 2,2'-IMINODIETHANOL (1:1)
Systematic Name English
Code System Code Type Description
PUBCHEM
44145550
Created by admin on Sat Dec 16 12:18:29 GMT 2023 , Edited by admin on Sat Dec 16 12:18:29 GMT 2023
PRIMARY
CAS
94200-76-7
Created by admin on Sat Dec 16 12:18:29 GMT 2023 , Edited by admin on Sat Dec 16 12:18:29 GMT 2023
PRIMARY
FDA UNII
4KQC35ZF1D
Created by admin on Sat Dec 16 12:18:29 GMT 2023 , Edited by admin on Sat Dec 16 12:18:29 GMT 2023
PRIMARY
EPA CompTox
DTXSID10240995
Created by admin on Sat Dec 16 12:18:29 GMT 2023 , Edited by admin on Sat Dec 16 12:18:29 GMT 2023
PRIMARY
ECHA (EC/EINECS)
303-556-5
Created by admin on Sat Dec 16 12:18:29 GMT 2023 , Edited by admin on Sat Dec 16 12:18:29 GMT 2023
PRIMARY