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Approval Year

Unknown
149124
Substance Class Nucleic Acid
Created
by admin
on Wed Apr 02 12:25:52 GMT 2025
Edited
by admin
on Wed Apr 02 12:25:52 GMT 2025
Nucleic Acid Type RNAI
Sequence Type COMPLETE
Record UNII
4KM8P975UM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Brogidirsen
USAN   INN  
Official Name English
NCNP-02
Preferred Name English
all-P-ambo-3'-deoxy-P-dimethylamino-2',3'-imino-2',3'-secothymidylyl-(2?a?5?)-P,3'-dideoxy-P-dimethylamino-2',3'-imino-2',3'-secothymidylyl-(2?a?5?)-P,2',3'-trideoxy-P-dimethylamino-2',3'-imino-2',3'-secoguanylyl-(2?a?5?)-P,3'-dideoxy-P-dimethylamino-2',
Common Name English
NS 089/NCNP 02
Code English
NS-089
Code English
RNA, [P-deoxy-P-(dimethylamino)](2?,3?-dideoxy-2?,3?-imino-2?,3?-seco)(2?a?5?)(m<sup>5</sup>U-m<sup>5</sup>U-G-m<sup>5</sup>U-G-m<sup>5</sup>U-C-m<sup>5</sup>U-m<sup>5</sup>U-m<sup>5</sup>U-C-m<sup>5</sup>U-m<sup>5</sup>U-C-m<sup>5</sup>U-G-m<sup>5</sup>
Common Name English
NS-089/NCNP-02
Code English
brogidirsen [INN]
Common Name English
NS 089/NCNP 02 (EXON 44 SKIPPING ANTISENSE OLIGONUCLEOTIDE)
Common Name English
BROGIDIRSEN [USAN]
Common Name English
Code System Code Type Description
USAN
MN-117
Created by admin on Wed Apr 02 12:25:52 GMT 2025 , Edited by admin on Wed Apr 02 12:25:52 GMT 2025
PRIMARY
INN
12240
Created by admin on Wed Apr 02 12:25:52 GMT 2025 , Edited by admin on Wed Apr 02 12:25:52 GMT 2025
PRIMARY
SMS_ID
300000046187
Created by admin on Wed Apr 02 12:25:52 GMT 2025 , Edited by admin on Wed Apr 02 12:25:52 GMT 2025
PRIMARY
FDA UNII
4KM8P975UM
Created by admin on Wed Apr 02 12:25:52 GMT 2025 , Edited by admin on Wed Apr 02 12:25:52 GMT 2025
PRIMARY
CAS
2409088-11-3
Created by admin on Wed Apr 02 12:25:52 GMT 2025 , Edited by admin on Wed Apr 02 12:25:52 GMT 2025
PRIMARY
NCI_THESAURUS
C190319
Created by admin on Wed Apr 02 12:25:52 GMT 2025 , Edited by admin on Wed Apr 02 12:25:52 GMT 2025
PRIMARY
Sugar Site Range Site Count
morpholino 1_1-1_24 24 / 24
Linkage Site Range Site Count
Phosphoryldimethylamine 1_2-1_24 23 / 23
Related Record Type Details
DYSTROPHIN
TARGET->ACTIVATOR OF EXPRESSION
Dystrophin expression stimulants
Related Record Type Details
Brogidirsen
ACTIVE MOIETY
NIH
NCATS
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