Denrakibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 17:01:35 GMT 2025` Edited by `admin` on `Wed Apr 02 17:01:35 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2\|IGG2A\|IGG2B\|IGG2A/B\|KAPPA
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	4K7FCQ266Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GSK-3858279

Preferred Name

English

Denrakibart

Official Name

English

H-gamma2 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV5-51*01 (98.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG2*01 G2m.. CH2 V45.1, G2v3 CH2 A1.2, A1, S2, A30, L92, S115, S116 (CH1 P92>T (193)

Common Name

English

denrakibart [INN]

Common Name

English

GSK3858279

Code

English

Immunoglobulin G2, anti-(human CC chemokine CCL17) (recombinant human monoclonal GSK3858279 ?2-chain), disulfide with recombinant human monoclonal GSK3858279 ?-chain, dimer

Common Name

English

immunoglobulin G2-kappa, anti-[Homo sapiens CCL17 (C-C motif chemokine ligand 17, chemokine (C-C motif) ligand 17, small inducible cytokine subfamily A (Cys-Cys) member 17, SCYA17, thymus and activation-regulated chemokine, TARC)], Homo sapiens monoclona

Common Name

English

Code System Code Type Description

INN

13177