Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H8Cl2N3O3.Na |
| Molecular Weight | 360.127 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].ClC1=CC=C(C=C1Cl)C2=CC=C(O2)\C=N\N3CC(=O)[N-]C3=O
InChI
InChIKey=ODQGDRHHSQIKSM-ZDEOBDHWSA-M
InChI=1S/C14H9Cl2N3O3.Na/c15-10-3-1-8(5-11(10)16)12-4-2-9(22-12)6-17-19-7-13(20)18-14(19)21;/h1-6H,7H2,(H,18,20,21);/q;+1/p-1/b17-6+;
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C14H9Cl2N3O3 |
| Molecular Weight | 338.146 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
Clodanolene is a skeletal muscle contraction antagonist, closely related to dantrolene sodium. The drug has no measurable direct effect on the peripheral or central nervous systems. In a mouse of muscle spasticity (Straub-tail mouse), clodanolene induced skeletal muscle relaxation more effectively than neuromuscular blocking agents, local anesthetics, or centrally-acting muscle relaxants. Indirect evidence indicates clodanolene acts on caffeine-sensitive calcium stores in the muscle cells.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:07:39 GMT 2023
by
admin
on
Fri Dec 15 18:07:39 GMT 2023
|
| Record UNII |
4ITZ0H29FL
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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68095-04-5
Created by
admin on Fri Dec 15 18:07:39 GMT 2023 , Edited by admin on Fri Dec 15 18:07:39 GMT 2023
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23664091
Created by
admin on Fri Dec 15 18:07:39 GMT 2023 , Edited by admin on Fri Dec 15 18:07:39 GMT 2023
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PRIMARY | |||
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4ITZ0H29FL
Created by
admin on Fri Dec 15 18:07:39 GMT 2023 , Edited by admin on Fri Dec 15 18:07:39 GMT 2023
|
PRIMARY |
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PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |