U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 06:22:46 GMT 2023
Edited
by admin
on Sat Dec 16 06:22:46 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
4H5YMK1H2E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BEZLOTOXUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
MK-6072
Code English
BEZLOTOXUMAB [MI]
Common Name English
BEZLOTOXUMAB [JAN]
Common Name English
MDX-1388
Code English
ZINPLAVA
Brand Name English
BEZLOTOXUMAB [PURPLE BOOK CDER]
Common Name English
BEZLOTOXUMAB [USAN]
Common Name English
MBL-CDB1
Code English
Bezlotoxumab [WHO-DD]
Common Name English
bezlotoxumab [INN]
Common Name English
Classification Tree Code System Code
WHO-ATC J06BB21
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
Code System Code Type Description
EVMPD
SUB127968
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
INN
9608
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
RXCUI
1855048
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
WIKIPEDIA
Bezlotoxumab
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
DAILYMED
4H5YMK1H2E
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
LACTMED
Bezlotoxumab
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
NCI_THESAURUS
C153084
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
ChEMBL
CHEMBL2108670
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
CAS
1246264-45-8
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
DRUG BANK
DB13140
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
USAN
YY-53
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
EPA CompTox
DTXSID601028182
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
DRUG CENTRAL
5186
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
ChEMBL
CHEMBL2109313
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
FDA UNII
4H5YMK1H2E
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
SMS_ID
100000153736
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
MERCK INDEX
m11977
Created by admin on Sat Dec 16 06:22:46 GMT 2023 , Edited by admin on Sat Dec 16 06:22:46 GMT 2023
PRIMARY
From To
1_22 1_96
1_146 1_202
1_263 1_323
1_369 1_427
2_22 2_96
2_146 2_202
2_263 2_323
2_369 2_427
3_23 3_89
3_135 3_195
4_23 4_89
4_135 4_195
1_222 3_215
2_222 4_215
1_228 2_228
1_231 2_231
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET -> INHIBITOR
TARGET ORGANISM->INHIBITOR
The rate of recurrent C. difficile infection was significantly lower with bezlotoxumab.
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
Volume of Distribution PHARMACOKINETIC
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Biological Half-life PHARMACOKINETIC