AVIZAKIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:54:05 GMT 2025` Edited by `admin` on `Wed Apr 02 01:54:05 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	4H3BBE5WVK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BOS-161721

Preferred Name

English

AVIZAKIMAB

Official Name

English

avizakimab [INN]

Common Name

English

Avizakimab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1 (251-TYROSINE,253-THREONINE,255-GLUTAMIC ACID), ANTI-(HUMAN INTERLEUKIN 21) (HUMAN-MUS MUSCULUS MONOCLONAL BOS161721 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BOS161721 .KAPPA.-CHAIN, DIMER

Common Name

English

BOS161721

Code

English

MEDI 7169 [WHO-DD]

Common Name

English

Code System Code Type Description

INN

11148

Created by admin on Wed Apr 02 01:54:05 GMT 2025 , Edited by admin on Wed Apr 02 01:54:05 GMT 2025

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SMS_ID

300000010834

Created by admin on Wed Apr 02 01:54:05 GMT 2025 , Edited by admin on Wed Apr 02 01:54:05 GMT 2025

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CAS

2229685-51-0

Created by admin on Wed Apr 02 01:54:05 GMT 2025 , Edited by admin on Wed Apr 02 01:54:05 GMT 2025

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NCI_THESAURUS

C171825

Created by admin on Wed Apr 02 01:54:05 GMT 2025 , Edited by admin on Wed Apr 02 01:54:05 GMT 2025

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FDA UNII

4H3BBE5WVK

Created by admin on Wed Apr 02 01:54:05 GMT 2025 , Edited by admin on Wed Apr 02 01:54:05 GMT 2025

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From	To
1_22	1_96
1_143	1_199
1_219	3_214
1_225	2_225
1_228	2_228
1_260	1_320
1_366	1_424
2_22	2_96
2_143	2_199
2_219	4_214
2_260	2_320
2_366	2_424
3_134	3_194
3_23	3_88
4_134	4_194
4_23	4_88

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					MKM3CA6LT1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					4H3BBE5WVK

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL