HEXAFLUMURON

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H8Cl2F6N2O3
Molecular Weight	461.143
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC(F)C(F)(F)OC1=C(Cl)C=C(NC(=O)NC(=O)C2=C(F)C=CC=C2F)C=C1Cl

InChI

InChIKey=RGNPBRKPHBKNKX-UHFFFAOYSA-N

InChI=1S/C16H8Cl2F6N2O3/c17-7-4-6(5-8(18)12(7)29-16(23,24)14(21)22)25-15(28)26-13(27)11-9(19)2-1-3-10(11)20/h1-5,14H,(H2,25,26,27,28)

HIDE SMILES / InChI

Molecular Formula	C16H8Cl2F6N2O3
Molecular Weight	461.143
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://npic.orst.edu/factsheets/hexgen.pdf | https://www.ncbi.nlm.nih.gov/pubmed/23917742

Hexaflumuron, a termite control product, is a chitin synthesis inhibitor. Chitin is the main component of the termite exoskeleton

Approval Year

PubMed

Title	Date	PubMed
Characterization of human cytochrome P450 induction by pesticides.	2012-03-29	22310298
Dissipation and evaluation of hexaflumuron residues in chinese cabbage grown in open fields.	2010-04-28	20345168
[Determination of benzoylurea and bishydrazide pesticide residues in vegetables by ultra performance liquid chromatography-tandem mass spectrometry with matrix solid phase dispersion].	2010-04	20712114
Synthesis and insecticidal activity of heptafluoroisopropyl-containing benzoylphenylurea structures.	2010-03-10	20014763
Impact of five commercial baits containing chitin synthesis inhibitors on the protist community in Reticulitermes flavipes (Isoptera: Rhinotermitidae).	2010-02	20146844
Laboratory evaluation of Flurox, a chitin synthesis inhibitor, on the termite, Microcerotermes diversus.	2010	20569123
Fate of organohalogens in US wastewater treatment plants and estimated chemical releases to soils nationwide from biosolids recycling.	2009-12	20024018
An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes.	2009-08	20183062
Design, synthesis, and bioactivity study of novel benzoylpyridazyl ureas.	2009-07-22	19601668
Determination of pesticides in water samples from the Wieprz-krzna Canal in the Leczyńsko-Włodawskie Lake District of southeastern Poland by thin-layer chromatography with diode array scanning and high-performance column liquid chromatography with diode array detection.	2008-11-05	18980142
Feeding preference of Coptotermes formosanus (Isoptera: Rhinotermitidae) for gamma-irradiated wood impregnated with benzoylphenylurea compounds under laboratory conditions.	2008-06	18613590
Phagostimulatory sugars enhance uptake and horizontal transfer of hexaflumuron in the western subterranean termite (Isoptera: Rhinotermitidae).	2008-06	18613589
Solid-phase microextraction for the determination of benzoylureas in orange juice using liquid chromatography combined with post-column photochemically induced fluorimetry derivatization and fluorescence detection.	2008-01	18069703
Field evaluation of potential control strategies against the invasive eastern subterranean termite (Isoptera: Rhinotermitidae) in Chile.	2007-08	17849893
Capabilities of different liquid chromatography tandem mass spectrometry systems in determining pesticide residues in food. Application to estimate their daily intake.	2007-07-20	17466998
Hermetically sealed baits for subterranean termites (Isoptera: Rhinotermitidae).	2007-04	17461073
New method for the photo-chemiluminometric determination of benzoylurea insecticides based on acetonitrile chemiluminescence.	2007-03	17205265
Laboratory evaluation of five chitin synthesis inhibitors against the colorado potato beetle, Leptinotarsa decemlineata.	2007	20345285
Toxicity of thiamethoxam against Philippine subterranean termites.	2007	20302537
Joint action of quercetin with four insecticides on the cotton leaf-worm larvae, Spodoptera littoralis Boisd. (Lep. : Noctuidae) in Egypt.	2007	18399473
Genetic differentiation in the soil-feeding termite Cubitermes sp. affinis subarquatus: occurrence of cryptic species revealed by nuclear and mitochondrial markers.	2006-11-23	17123444
Fragmentation study and analysis of benzoylurea insecticides and their analogs by liquid chromatography-electrospray ionization-mass spectrometry.	2006-08-15	18970732
Laboratory evaluation of bistrifluron, a benzoylphenylurea compound, as a bait toxicant against Coptotermes formosanus (Isoptera: Rhinotermitidae).	2006-08	16937693
Effects of insect growth regulators on the nontarget soil arthropod Folsomia candida (Collembola).	2006-02	16112194
Determination of benzoylureas in ground water samples by fully automated on-line pre-concentration and liquid chromatography-fluorescence detection.	2006-01-27	16337641
Routine application using single quadrupole liquid chromatography-mass spectrometry to pesticides analysis in citrus fruits.	2005-09-23	16130755
Elimination and reinvasion studies with Coptotermes formosanus (Isoptera: Rhinotermitidae) in Louisiana.	2005-06	16022322
Effect of hexaflumuron on mortality of the Western subterranean termite (Isoptera: Rhinotermitidae) during and following exposure and movement of hexaflumuron in termite groups.	2005-06	15657953
Comparison of liquid chromatography using triple quadrupole and quadrupole ion trap mass analyzers to determine pesticide residues in oranges.	2005-03-04	15844516
Determination of seven benzoylphenylurea insecticides in processed fruit and vegetables using high-performance liquid chromatography/tandem mass spectrometry.	2005	16136517
Disruption of reproductive activity of Coptotermes formosanus (Isoptera: Rhinotermitidae) primary reproductives by three chitin synthesis inhibitors.	2004-12	15666759
Laboratory performance and pharmacokinetics of the benzoylphenylurea noviflumuron in eastern subterranean termites (Isoptera: Rhinotermitidae).	2004-04	15154487
Benzoylphenylurea residues in peppers and zucchinis grown in greenhouses: determination of decline times and pre-harvest intervals by modelling.	2004-02	14971687
Persistence and residual activity of an organophosphate, pirimiphos-methyl, and three IGRs, hexaflumuron, teflubenzuron and pyriproxyfen, against the cowpea weevil, Callosobruchus maculatus (Coleoptera: Bruchidae).	2004-01	14727746
Laboratory evaluation of selective pesticides against the storage mite Tyrophagus putrescentiae (Acari: Acaridae).	2003-07	14680114
Determination of five pesticide residues in oranges by matrix solid-phase dispersion and liquid chromatography to estimate daily intake of consumers.	2001-06-22	11417653
Determination of benzoylureas in tomato by high-performance liquid chromatography using continuous on-line post-elution photoirradiation with fluorescence detection.	2001-05-18	11403458
Bait matrix for delivery of chitin synthesis inhibitors to the formosan subterranean termite (Isoptera: Rhinotermitidae).	2001-04	11332846
Photochemical-spectrofluorimetric method for the determination of benzoylurea insecticides: applications in river water samples and in technical formulations.	2001-01-26	18968181

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:54:55 GMT 2025` Edited by `admin` on `Mon Mar 31 18:54:55 GMT 2025`
Record UNII	4GW50R449T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RECRUIT

Preferred Name

English

HEXAFLUMURON

Common Name

English

1-(3,5-DICHLORO-4-(1,1,2,2-TETRAFLUOROETHOXY) PHENYL)-3-(2,6-DIFLUOROBENZOYL)UREA

Systematic Name

English

N-(((3,5-DICHLORO-4-(1,1,2,2-TETRAFLUOROETHOXY)PHENYL)AMINO)CARBONYL)-2,6-DIFLUOROBENZAMIDE

Systematic Name

English

HEXAFLUMURON [MI]

Common Name

English

HEXAFLUMURON [ISO]

Common Name

English

1-(3,5-DICHLORO-4-(1,1,2,2-TETRAFLUOROETHOXY)PHENYL)-3-(2,6-DIFLUOROBENZOYL)UREA

Systematic Name

English

XRD-473

Code

English

DE-473

Code

English

HEXAFLUMURON [HSDB]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

118202