ISOPREDNIDENE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H28O5
Molecular Weight	372.4547
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC(=C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])C=CC4=CC(=O)CC[C@]34C

InChI

InChIKey=MAAGHJOYEMWLNT-CWNVBEKCSA-N

InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h4-5,9,15-17,19,23,25,27H,1,6-8,10-11H2,2-3H3/t15-,16-,17-,19+,20-,21-,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H28O5
Molecular Weight	372.4547
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4320513 | https://www.ncbi.nlm.nih.gov/pubmed/4317302

ISOPREDNIDENE is a synthetic glucocorticoid. It suppresses both the release and the synthesis of adrenocorticotropin by the pituitary gland.

CNS Activity

Approval Year

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:02:00 UTC 2023` Edited by `admin` on `Sat Dec 16 17:02:00 UTC 2023`
Record UNII	4G6A72XC0I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISOPREDNIDENE

Official Name

English

11.BETA.,17,21-TRIHYDROXY-16-METHYLENEPREGNA-4,6-DIENE-3,20-DIONE

Systematic Name

English

isoprednidene [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C521