BROPARESTROL (E)-

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H19Br
Molecular Weight	363.29
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC1=CC=C(C=C1)C(=C(\Br)C2=CC=CC=C2)\C3=CC=CC=C3

InChI

InChIKey=OQCYTSHIQNPJIC-QURGRASLSA-N

InChI=1S/C22H19Br/c1-2-17-13-15-19(16-14-17)21(18-9-5-3-6-10-18)22(23)20-11-7-4-8-12-20/h3-16H,2H2,1H3/b22-21+

HIDE SMILES / InChI

Molecular Formula	C22H19Br
Molecular Weight	363.29
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2604956 | https://www.ncbi.nlm.nih.gov/pubmed/4084664 | https://www.ncbi.nlm.nih.gov/pubmed/12305430 |

Broparestrol, (Z)- is an isomer of Broparestrol -- synthetic, nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that has been used in Europe as a dermatological agent and for the treatment of breast cancer. Broparestrol, (Z)- and Broparestrol, (E)- demonstrates antiestrogenic activity but, unlike broparestrol, were never marketed.

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:09:25 GMT 2025` Edited by `admin` on `Mon Mar 31 21:09:25 GMT 2025`
Record UNII	4F4UXV47YI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LN-1643

Preferred Name

English

BROPARESTROL (E)-

Common Name

English

TRANS-BROPARESTROL

Common Name

English

ETHYLENE, 1-BROMO-2-(P-ETHYLPHENYL)-1,2-DIPHENYL-, (E)-

Common Name

English

BROPARESTROL (E)-FORM [MI]

Common Name

English

(E)-BROPARESTROL

Common Name

English

BENZENE, 1-(2-BROMO-1,2-DIPHENYLETHENYL)-4-ETHYL-, (E)-

Common Name

English

1-(2-BROMO-1,2-DIPHENYLETHENYL)-4-ETHYLBENZENE, (E)-

Systematic Name

English

Code System Code Type Description

CAS

22393-62-0