Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H24N2O3 |
| Molecular Weight | 340.4162 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C(C=CN=C2C=C1)[C@@H](O)[C@@H]3C[C@@H]4CC[N@]3C[C@]4(O)C=C
InChI
InChIKey=BSRUJCFCZKMFMB-YGHPHNMRSA-N
InChI=1S/C20H24N2O3/c1-3-20(24)12-22-9-7-13(20)10-18(22)19(23)15-6-8-21-17-5-4-14(25-2)11-16(15)17/h3-6,8,11,13,18-19,23-24H,1,7,9-10,12H2,2H3/t13-,18-,19+,20+/m0/s1
| Molecular Formula | C20H24N2O3 |
| Molecular Weight | 340.4162 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Quinine distribution in pregnant mice with Plasmodium berghei malaria. | 2006 Jul |
|
| Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers. | 2007 Feb |
|
| Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. | 2008 Oct |
|
| Variable inhibitory effect of different brands of commercial herbal supplements on human cytochrome P-450 CYP3A4. | 2009 |
|
| Simultaneous liquid chromatographic analysis of ritonavir, quinine and 3-hydroxyquinine in human plasma. | 2009 Feb 1 |
|
| Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women. | 2010 Dec |
|
| Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans. | 2010 Jun |
|
| Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration. | 2010 Mar |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:41:46 GMT 2025
by
admin
on
Mon Mar 31 21:41:46 GMT 2025
|
| Record UNII |
4D7695509M
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
17685
Created by
admin on Mon Mar 31 21:41:46 GMT 2025 , Edited by admin on Mon Mar 31 21:41:46 GMT 2025
|
PRIMARY | |||
|
157225
Created by
admin on Mon Mar 31 21:41:46 GMT 2025 , Edited by admin on Mon Mar 31 21:41:46 GMT 2025
|
PRIMARY | |||
|
DTXSID901316798
Created by
admin on Mon Mar 31 21:41:46 GMT 2025 , Edited by admin on Mon Mar 31 21:41:46 GMT 2025
|
PRIMARY | |||
|
4D7695509M
Created by
admin on Mon Mar 31 21:41:46 GMT 2025 , Edited by admin on Mon Mar 31 21:41:46 GMT 2025
|
PRIMARY | |||
|
58234
Created by
admin on Mon Mar 31 21:41:46 GMT 2025 , Edited by admin on Mon Mar 31 21:41:46 GMT 2025
|
PRIMARY | |||
|
78549-61-8
Created by
admin on Mon Mar 31 21:41:46 GMT 2025 , Edited by admin on Mon Mar 31 21:41:46 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE LESS ACTIVE |
