Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C20H24N2O3 |
Molecular Weight | 340.4162 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C(C=CN=C2C=C1)[C@@H](O)[C@@H]3C[C@@H]4CC[N@]3C[C@]4(O)C=C
InChI
InChIKey=BSRUJCFCZKMFMB-YGHPHNMRSA-N
InChI=1S/C20H24N2O3/c1-3-20(24)12-22-9-7-13(20)10-18(22)19(23)15-6-8-21-17-5-4-14(25-2)11-16(15)17/h3-6,8,11,13,18-19,23-24H,1,7,9-10,12H2,2H3/t13-,18-,19+,20+/m0/s1
Molecular Formula | C20H24N2O3 |
Molecular Weight | 340.4162 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Quinine distribution in pregnant mice with Plasmodium berghei malaria. | 2006 Jul |
|
Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers. | 2007 Feb |
|
Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. | 2008 Oct |
|
Variable inhibitory effect of different brands of commercial herbal supplements on human cytochrome P-450 CYP3A4. | 2009 |
|
Simultaneous liquid chromatographic analysis of ritonavir, quinine and 3-hydroxyquinine in human plasma. | 2009 Feb 1 |
|
Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women. | 2010 Dec |
|
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans. | 2010 Jun |
|
Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration. | 2010 Mar |
Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:41:46 GMT 2025
by
admin
on
Mon Mar 31 21:41:46 GMT 2025
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Record UNII |
4D7695509M
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Record Status |
Validated (UNII)
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Record Version |
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Related Record | Type | Details | ||
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PARENT -> METABOLITE LESS ACTIVE |