Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H9FN2O3 |
| Molecular Weight | 200.1671 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
FC1=CN([C@@H]2CCCO2)C(=O)NC1=O
InChI
InChIKey=WFWLQNSHRPWKFK-LURJTMIESA-N
InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)/t6-/m0/s1
| Molecular Formula | C8H9FN2O3 |
| Molecular Weight | 200.1671 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Dual modulation of UFT with leucovorin and hydroxyurea in metastatic colorectal cancer. | 2001 |
|
| The oral fluorinated pyrimidines. | 2001 |
|
| [5-fluorouracil and dihydropyrimidine dehydrogenase]. | 2001 Apr |
|
| New options for outpatient chemotherapy--the role of oral fluoropyrimidines. | 2001 Aug |
|
| [Postoperative chemotherapy with a novel oral anticancer drug composed of tegafur, gimeracil and oteracil potassium to curability C scirrhus type gastric cancer]. | 2001 Aug |
|
| Simultaneous determination of F-beta-alanine and beta-alanine in plasma and urine with dual-column reversed-phase high-performance liquid chromatography. | 2001 Aug 5 |
|
| Pathologic downstaging of T3-4Nx rectal cancer after chemoradiation: 5-fluorouracil vs. Tegafur. | 2001 Dec 1 |
|
| National Surgical Adjuvant Breast and Bowel Project trials in colon cancer. | 2001 Feb |
|
| A phase II trial of oral UFT plus cisplatin (CDDP) in patients with non-small cell lung cancer (NSCLC). | 2001 Feb-Mar |
|
| Other fluorinated pyrimidines in the treatment of solid tumors. | 2001 Jan |
|
| [Long survival in a case of unresectable hepatic metastasis from rectal carcinoma treated with second-look hepatectomy plus pharmacokinetic modulating chemotherapy (PMC)]. | 2001 Jan |
|
| [New drugs for colorectal cancer: UFT]. | 2001 Jan-Feb |
|
| Methylenetetrahydrofolate reductase polymorphism is associated with folate pool in gastrointestinal cancer tissue. | 2001 Jan-Feb |
|
| Postsurgical sequential methotrexate/5-FU and leucovorin on outpatient basis for advanced colorectal carcinoma. | 2001 Jan-Feb |
|
| [Two elderly patients with advanced gastric cancer responding to chronomodulation chemotherapy with tegafur + cisplatin + isovorin followed by oral administration of S-1]. | 2001 Jul |
|
| Effects of 5-fluorouracil on the drug-metabolizing enzymes of the small intestine and the consequent drug interaction with nifedipine in rats. | 2001 Jun |
|
| Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long-term prognosis in cirrhotic patients: metaanalysis of three randomized controlled trials. | 2001 Jun 15 |
|
| UFT-induced haemolytic anaemia. | 2001 Mar |
|
| Effect of food on the oral bioavailability of UFT and leucovorin in cancer patients. | 2001 Mar |
|
| [A case of advanced gastric cancer complicated with liver metastases responding remarkably to combined chemotherapy with 5-fluorouracil and low-dose cisplatin, with UFT and low-dose cisplatin for maintenance on an outpatient basis]. | 2001 Mar |
|
| [Long-term survival of hormone-refractory prostate cancer: a case report]. | 2001 Mar 1 |
|
| Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur. | 2001 May |
|
| Intestinal permeability in patients with chemotherapy-induced stomatitis. | 2001 May |
|
| [A case of squamous cell carcinoma of the oral floor showing a complete response to oral administration of UFT]. | 2001 Nov |
|
| [A case of breast cancer with multiple metastases effectively treated with long-term administration of docetaxel, aclarubicin and UFT]. | 2001 Nov |
|
| [Efficacy of intraperitoneal chemotherapy for peritoneal recurrence of gastric carcinoma]. | 2001 Oct |
|
| Nonsurgical treatment of hepatocellular carcinoma. | 2001 Oct |
|
| [A case report of rectal cancer with liver and pulmonary metastases responding to TS-1]. | 2001 Oct |
|
| [Late phase II study of S-1 in patients with advanced head and neck cancer]. | 2001 Oct |
|
| Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases. | 2001 Sep-Oct |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:53:19 GMT 2023
by
admin
on
Sat Dec 16 09:53:19 GMT 2023
|
| Record UNII |
4D5LOR404U
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
4D5LOR404U
Created by
admin on Sat Dec 16 09:53:19 GMT 2023 , Edited by admin on Sat Dec 16 09:53:19 GMT 2023
|
PRIMARY | |||
|
148755
Created by
admin on Sat Dec 16 09:53:19 GMT 2023 , Edited by admin on Sat Dec 16 09:53:19 GMT 2023
|
PRIMARY | |||
|
55774-30-6
Created by
admin on Sat Dec 16 09:53:19 GMT 2023 , Edited by admin on Sat Dec 16 09:53:19 GMT 2023
|
PRIMARY |